Sedimentation rate (ESR): normal values, causes of elevation and interpretation | Clinique Omicron<\/title>\n<meta name=\"description\" content=\"La vitesse de s\u00e9dimentation mesure l'inflammation non sp\u00e9cifiquement. VS \u00e9lev\u00e9e causes, art\u00e9rite temporale VS >50mm\/h urgence, my\u00e9lome, VS normale avec CRP \u00e9lev\u00e9e et interpr\u00e9tation au Qu\u00e9bec.\">\n<meta name=\"keywords\" content=\"vitesse de s\u00e9dimentation, VS, VS \u00e9lev\u00e9e causes, s\u00e9dimentation art\u00e9rite temporale, VS normale CRP, VS my\u00e9lome, VS grossesse, VS an\u00e9mie, vitesse s\u00e9dimentation interpr\u00e9tation, VS Qu\u00e9bec\">\n<link rel=\"preconnect\" href=\"https:\/\/fonts.googleapis.com\">\n<link href=\"https:\/\/fonts.googleapis.com\/css2?family=Cinzel:wght@600&family=Poppins:wght@400;500;600;700&display=swap\" rel=\"stylesheet\">\n<style>\n@import url('https:\/\/fonts.googleapis.com\/css2?family=Cinzel:wght@600&family=Poppins:wght@400;500;600;700&display=swap');\n\n.co-wrap * {\n font-family: 'Poppins', sans-serif;\n box-sizing: border-box;\n}\n.co-wrap {\n max-width: 1100px;\n margin: 0 auto;\n padding: 30px 0 60px;\n margin-top: 10px;\n}\n.co-label {\n font-family: 'Cinzel', serif;\n font-size: 14px;\n font-weight: bold;\n letter-spacing: 1px;\n text-transform: uppercase;\n color: #4D6577;\n margin-bottom: 14px;\n display: block;\n}\n.co-wrap h1 {\n font-size: 32px;\n font-weight: 500;\n color: #323C52;\n margin: 0 0 22px;\n line-height: 1.2;\n letter-spacing: 0.5px;\n}\n.co-intro {\n font-size: 16px;\n font-weight: 400;\n line-height: 1.75;\n color: #4D6577;\n margin-bottom: 36px;\n padding-bottom: 32px;\n border-bottom: 1px solid rgba(77,101,119,.2);\n}\n.co-wrap h2 {\n font-size: 20px;\n font-weight: 600;\n color: #323C52;\n margin: 32px 0 12px;\n letter-spacing: 0.3px;\n}\n.co-wrap p {\n font-size: 15px;\n font-weight: 400;\n color: #4D6577;\n line-height: 1.7;\n margin-bottom: 14px;\n}\n.co-list {\n list-style: none;\n padding: 0;\n margin: 12px 0 24px;\n}\n.co-list li {\n font-size: 15px;\n font-weight: 400;\n color: #4D6577;\n padding: 10px 14px 10px 38px;\n margin-bottom: 8px;\n border-radius: 6px;\n position: relative;\n background: rgba(77,101,119,.06);\n border-left: 3px solid #4D6577;\n}\n.co-list li::before {\n content: \"\u2713\";\n position: absolute;\n left: 12px;\n font-weight: 700;\n color: #4D6577;\n}\n.co-table {\n width: 100%;\n border-collapse: collapse;\n margin: 14px 0 22px;\n font-size: 14px;\n border-radius: 8px;\n overflow: hidden;\n}\n.co-table thead tr {\n background: #323C52;\n color: #fff;\n}\n.co-table thead th {\n padding: 11px 16px;\n text-align: left;\n font-weight: 600;\n font-size: 13px;\n}\n.co-table tbody tr:nth-child(even) {\n background: rgba(77,101,119,.06);\n}\n.co-table tbody tr:nth-child(odd) {\n background: #fff;\n}\n.co-table td {\n padding: 10px 16px;\n color: #4D6577;\n border-bottom: 1px solid rgba(77,101,119,.12);\n font-size: 14px;\n vertical-align: top;\n}\n.co-table td:first-child {\n font-weight: 600;\n color: #323C52;\n}\n.co-infobox {\n display: flex;\n gap: 12px;\n background: rgba(77,101,119,.06);\n border-radius: 8px;\n border-left: 4px solid #4D6577;\n padding: 14px 18px;\n margin: 18px 0 28px;\n font-size: 14px;\n font-weight: 400;\n color: #4D6577;\n line-height: 1.65;\n}\n.co-infobox .ico {\n font-size: 18px;\n flex-shrink: 0;\n}\n.co-urgence {\n background: #fff8f8;\n border-left: 5px solid #c0392b;\n border-radius: 6px;\n padding: 20px 26px;\n margin: 24px 0 32px;\n}\n.co-urgence .co-urgence-titre {\n font-size: 13px;\n font-weight: 700;\n color: #c0392b;\n letter-spacing: 1.5px;\n text-transform: uppercase;\n margin-bottom: 10px;\n}\n.co-urgence p {\n color: #5a2020;\n font-size: 14px;\n margin: 0 0 10px;\n line-height: 1.7;\n}\n.co-urgence p:last-child {\n margin-bottom: 0;\n}\n.co-disclaimer {\n font-size: 13px;\n color: #8a9aaa;\n font-style: italic;\n border-top: 1px solid rgba(77,101,119,.15);\n padding-top: 24px;\n margin-top: 40px;\n line-height: 1.6;\n}\n<\/style>\n<\/head>\n<body>\n<div class=\"co-wrap\">\n\n <span class=\"co-label\">Biochimie clinique & Rhumatologie & M\u00e9decine de famille<\/span>\n <h1>Vitesse de s\u00e9dimentation (VS)<\/h1>\n\n <div class=\"co-intro\">\n La vitesse de s\u00e9dimentation des \u00e9rythrocytes (VSE) \u2014 commun\u00e9ment abr\u00e9g\u00e9e VS ou ESR (<em>Erythrocyte Sedimentation Rate<\/em> is one of the oldest and most widely used biological tests in clinical medicine: it measures the distance (in millimeters) traveled by erythrocytes to the bottom of a standardized vertical anticoagulated blood tube in 1 hour (Westergren method - 200 mm tube filled with citrated blood + reading at 1 hour). Erythrocytes sediment slowly under normal conditions, as their negative surface charge (zeta-potential - sialic acid) confers a mutual electrostatic repulsion that opposes aggregation. The SV is accelerated when high-molecular-weight plasma proteins - mainly fibrinogen (positive acute-phase reactant + increases in 24-48 h during inflammation) + immunoglobulins (IgG + IgA + IgM - increases in chronic infections + gammopathies + autoimmune diseases) + and the alpha-2 globulin fraction - adsorb to the surface of erythrocytes, reduce their zeta-potential and promote their aggregation into more rapidly sedimenting rolls. The VS is thus an indirect, non-specific marker of systemic inflammation - whose great strength lies in its sensitivity for detecting chronic inflammations (polymyalgia rheumatica + giant cell arteritis + myeloma + chronic infections) + and its great weakness in its lack of specificity (elevated in pregnancy + anemia + obesity + advanced age + acute infections + cancers + autoimmune diseases) and its slow response (rises in 24-48 h + remains elevated for weeks even after resolution of inflammation - unlike CRP, which normalizes in 3-5 days). The SV must always be interpreted in conjunction with the CRP and in the clinical context - the two markers are complementary, not redundant.\n <\/div>\n\n <h2>Valeurs normales selon l'\u00e2ge et le sexe<\/h2>\n <ul class=\"co-list\">\n <li><strong>Formule de Miller (estimation rapide des limites sup\u00e9rieures normales) :<\/strong> homme = \u00e2ge \/ 2 + femme = (\u00e2ge + 10) \/ 2 \u2192 exemples : homme 50 ans \u2192 VS < 25 mm\/h + femme 50 ans \u2192 VS < 30 mm\/h + homme 70 ans \u2192 VS < 35 mm\/h + femme 70 ans \u2192 VS < 40 mm\/h<\/li>\n <li><strong>Valeurs normales de r\u00e9f\u00e9rence usuelles :<\/strong> homme < 50 ans : < 15 mm\/h + homme > 50 ans : < 20 mm\/h + femme < 50 ans : < 20 mm\/h + femme > 50 ans : < 30 mm\/h + enfant : < 10\u201315 mm\/h<\/li>\n <li><strong>VS l\u00e9g\u00e8rement \u00e9lev\u00e9e (20\u201350 mm\/h) :<\/strong> variable clinical significance + can be physiological in the elderly + pregnant women + or pathological in many mild to moderate conditions<\/li>\n <li><strong>VS mod\u00e9r\u00e9ment \u00e9lev\u00e9e (50\u2013100 mm\/h) :<\/strong> significant + suggests active infection + chronic inflammatory disease + neoplasia<\/li>\n <li><strong>VS tr\u00e8s \u00e9lev\u00e9e (> 100 mm\/h) :<\/strong> clinically very important threshold value \u2192 90 % of cases have an identifiable serious cause \u2192 systematic in-depth workup \u2192 giant cell arteritis (GCA) ++ + multiple myeloma ++ + severe infections + severe autoimmune diseases + lymphomas<\/li>\n <\/ul>\n\n <h2>Causes d'\u00e9l\u00e9vation de la VS<\/h2>\n\n <table class=\"co-table\">\n <thead>\n <tr>\n <th>Category<\/th>\n <th>Main causes<\/th>\n <th>Mechanism and context<\/th>\n <\/tr>\n <\/thead>\n <tbody>\n <tr>\n <td>Inflammatory rheumatological diseases<\/td>\n <td>Art\u00e9rite \u00e0 cellules g\u00e9antes (ACG \u2014 art\u00e9rite temporale) ++ + polymyalgie rhumatismale (PMR) ++ + polyarthrite rhumato\u00efde + lupus + spondylarthrite axiale + vascularites + connectivites<\/td>\n <td>ACG et PMR : VS souvent > 50\u2013100 mm\/h + VS = crit\u00e8re diagnostique majeur de l'ACG + aussi crit\u00e8re de suivi du traitement par cortico\u00efdes (normalisation attendue sous traitement)<\/td>\n <\/tr>\n <tr>\n <td>Infections aigu\u00ebs et chroniques<\/td>\n <td>Infections bact\u00e9riennes s\u00e9v\u00e8res + endocardite infectieuse + ost\u00e9omy\u00e9lite + tuberculose + abc\u00e8s profonds + infections chroniques \u00e0 VIH + VHC + VHB<\/td>\n <td>Fibrinog\u00e8ne augmente en 24\u201348 h lors de l'infection \u2192 VS \u00e9lev\u00e9e + moins sensible que la CRP pour les infections aigu\u00ebs + mais utile pour les infections chroniques (tuberculose + endocardite)<\/td>\n <\/tr>\n <tr>\n <td>H\u00e9mopathies malignes<\/td>\n <td>My\u00e9lome multiple +++ (immunoglobulines monoclonales en tr\u00e8s grande quantit\u00e9) + macroglobulin\u00e9mie de Waldenstr\u00f6m + lymphomes<\/td>\n <td>My\u00e9lome : cause classique de VS tr\u00e8s \u00e9lev\u00e9e (> 100 mm\/h) par accumulation d'immunoglobulines monoclonales \u2192 \u00e9lectrophor\u00e8se des prot\u00e9ines s\u00e9riques syst\u00e9matique si VS inexpliqu\u00e9e > 100 mm\/h<\/td>\n <\/tr>\n <tr>\n <td>Solid cancers<\/td>\n <td>Cancer du rein + cancer du poumon + cancer colorectal + cancer gastrique + m\u00e9tastases + paran\u00e9oplasique<\/td>\n <td>\u00c9l\u00e9vation mod\u00e9r\u00e9e \u00e0 s\u00e9v\u00e8re + m\u00e9canisme : prot\u00e9ines de phase aigu\u00eb + n\u00e9crose + inflammation + doit \u00eatre \u00e9voqu\u00e9 si VS \u00e9lev\u00e9e sans autre explication \u00e9vidente + surtout apr\u00e8s 50 ans<\/td>\n <\/tr>\n <tr>\n <td>Physiological (non-pathological) causes<\/td>\n <td>Grossesse (2e\u20133e trimestre) + menstruation + \u00e2ge avanc\u00e9 + ob\u00e9sit\u00e9<\/td>\n <td>Grossesse : VS peut atteindre 40\u201370 mm\/h normalement (fibrinog\u00e8ne augmente physiologiquement) + grand \u00e2ge : VS tend \u00e0 augmenter avec l'\u00e2ge m\u00eame sans pathologie \u2192 utiliser la formule de Miller pour ajuster les normales<\/td>\n <\/tr>\n <tr>\n <td>Anemia<\/td>\n <td>Toute cause d'an\u00e9mie \u2192 VS augment\u00e9e par m\u00e9canisme physique<\/td>\n <td>Moins d'\u00e9rythrocytes \u2192 moins de r\u00e9pulsion \u2192 s\u00e9dimentation plus rapide \u2192 correction : la VS doit \u00eatre interpr\u00e9t\u00e9e en tenant compte de l'h\u00e9matocrite (h\u00e9matocrite bas = VS artificiellement \u00e9lev\u00e9e)<\/td>\n <\/tr>\n <tr>\n <td>Chronic renal failure<\/td>\n <td>IRC \u2192 accumulation de prot\u00e9ines inflammatoires + an\u00e9mie + hypoalbumin\u00e9mie<\/td>\n <td>VS souvent mod\u00e9r\u00e9ment \u00e9lev\u00e9e dans l'IRC \u2192 moins sp\u00e9cifique pour le diagnostic d'une inflammation surajout\u00e9e<\/td>\n <\/tr>\n <\/tbody>\n <\/table>\n\n <h2>Causes de VS basse ou normale malgr\u00e9 inflammation \u2014 faux n\u00e9gatifs<\/h2>\n <ul class=\"co-list\">\n <li><strong>Polyglobulin :<\/strong> very high hematocrit \u2192 RBCs are too numerous \u2192 repulsion between RBCs dominates \u2192 slowed sedimentation \u2192 falsely normal or low ESR even if inflammation is real<\/li>\n <li><strong>Cryoglobulin\u00e9mie + hypofibrinog\u00e9n\u00e9mie + CIVD :<\/strong> abnormal or reduced proteins \u2192 lowered VS<\/li>\n <li><strong>Dr\u00e9panocytose :<\/strong> Sickle RBCs do not stack in rolls \u2192 very low SV<\/li>\n <li><strong>Insuffisance cardiaque congestive s\u00e9v\u00e8re :<\/strong> hypervolemia \u2192 protein dilution \u2192 lowered VS<\/li>\n <li><strong>Active lupus :<\/strong> paradoxically, relapsing lupus may have a normal or low SV (immune complexes + cryoglobulins + fibrinogen consumption in associated DIC) \u2192 CRP is a better marker of lupus activity<\/li>\n <\/ul>\n\n <div class=\"co-infobox\">\n <span class=\"ico\">\u2119\ufe0f<\/span>\n <span>VS vs CRP \u2014 utilisation compl\u00e9mentaire : la CRP est un marqueur d'inflammation aigu\u00eb (monte en 6\u201312 h + se normalise en 3\u20135 jours + peu influenc\u00e9e par l'an\u00e9mie + la grossesse + l'\u00e2ge) tandis que la VS refl\u00e8te une inflammation chronique ou subaigu\u00eb (monte lentement en 24\u201348 h + reste \u00e9lev\u00e9e des semaines + tr\u00e8s influenc\u00e9e par l'an\u00e9mie + la grossesse + les immunoglobulines). Dans l'art\u00e9rite temporale et la PMR, les deux marqueurs sont \u00e9lev\u00e9s et utilis\u00e9s conjointement pour le diagnostic et le suivi. Dans le lupus, la CRP peut \u00eatre normale m\u00eame en pouss\u00e9e (sauf si infection bact\u00e9rienne) tandis que la VS est souvent \u00e9lev\u00e9e. Dans les infections aigu\u00ebs, la CRP est plus sensible et plus rapide que la VS.<\/span>\n <\/div>\n\n <h2>La VS dans l'art\u00e9rite \u00e0 cellules g\u00e9antes (ACG) \u2014 utilisation clinique cruciale<\/h2>\n <ul class=\"co-list\">\n <li><strong>Typical presentation:<\/strong> femme > 50 ans (pic 70\u201380 ans) + c\u00e9phal\u00e9es temporales + art\u00e8re temporale douloureuse et indur\u00e9e + claudication de la m\u00e2choire + troubles visuels (amaurose fugace \u2192 c\u00e9cit\u00e9 d\u00e9finitive si non trait\u00e9e) + polymyalgie rhumatismale associ\u00e9e dans 50 % des cas<\/li>\n <li><strong>VS dans l'ACG :<\/strong> VS > 50 mm\/h est un crit\u00e8re ACR majeur de l'ACG + VS > 100 mm\/h est tr\u00e8s \u00e9vocatrice + mais 5\u201310 % des ACG ont une VS normale \u2192 ne pas exclure le diagnostic sur une VS normale si forte suspicion clinique \u2192 biopsie de l'art\u00e8re temporale + \u00e9cho-Doppler des art\u00e8res temporales + PET-TDM<\/li>\n <li><strong>Urgent treatment (do not wait for biopsy):<\/strong> prednisone 60 mg\/day per os as soon as clinical suspicion arises \u2192 prevention of irreversible blindness \u2192 biopsy remains positive for 2-4 weeks on corticosteroids<\/li>\n <li><strong>Treatment follow-up :<\/strong> VS and CRP normalize on corticosteroids in 2-4 weeks \u2192 monthly monitoring to guide the decrease + a further rise suggests a relapse<\/li>\n <\/ul>\n\n <div class=\"co-urgence\">\n <div class=\"co-urgence-titre\">Urgent medical consultation<\/div>\n <p>Consulter un m\u00e9decin dans les 24 heures si une VS tr\u00e8s \u00e9lev\u00e9e (> 100 mm\/h) est d\u00e9couverte sans cause \u00e9vidente \u2014 ce r\u00e9sultat justifie un bilan approfondi (\u00e9lectrophor\u00e8se des prot\u00e9ines + NFS + CRP + bilan r\u00e9nal + h\u00e9patique + imagerie selon le contexte). Consulter en urgence imm\u00e9diate si la VS \u00e9lev\u00e9e s'accompagne de c\u00e9phal\u00e9es temporales + de troubles visuels + de claudication de la m\u00e2choire chez une personne de plus de 50 ans \u2014 ce tableau \u00e9voque une art\u00e9rite \u00e0 cellules g\u00e9antes, urgence ophtalmologique n\u00e9cessitant des cortico\u00efdes en urgence pour pr\u00e9venir la c\u00e9cit\u00e9. Pour la prescription et l'interpr\u00e9tation de la VS, Clinique Omicron offre des consultations dans ses points de service au Qu\u00e9bec et en t\u00e9l\u00e9m\u00e9decine. Pour prendre rendez-vous, visitez <a href=\"https:\/\/cliniqueomicron.ca\" style=\"color:#c0392b;font-weight:600;text-decoration:none;\">cliniqueomicron.ca<\/a>.<\/p>\n <\/div>\n\n <h2>Consult at Clinique Omicron<\/h2>\n <p>Les m\u00e9decins et infirmiers praticiens sp\u00e9cialis\u00e9s (IPS) de Clinique Omicron prescrivent et interpr\u00e8tent la VS dans son contexte clinique en l'associant \u00e0 la CRP, \u00e0 la NFS et aux autres marqueurs inflammatoires, distinguent les causes physiologiques des causes pathologiques d'\u00e9l\u00e9vation, prescrivent le bilan d'investigation appropri\u00e9 selon le niveau de VS et les signes cliniques associ\u00e9s, initient les cortico\u00efdes en urgence si une art\u00e9rite \u00e0 cellules g\u00e9antes est suspect\u00e9e, et orientent vers la rhumatologie + l'h\u00e9matologie ou l'oncologie selon l'\u00e9tiologie identifi\u00e9e. Des consultations sont disponibles dans plusieurs points de service au Qu\u00e9bec et en t\u00e9l\u00e9m\u00e9decine. Pour prendre rendez-vous, visitez <a href=\"https:\/\/cliniqueomicron.ca\" style=\"color:#4D6577;font-weight:600;text-decoration:none;\">cliniqueomicron.ca<\/a>.<\/p>\n\n <p class=\"co-disclaimer\">Le contenu de cette page est fourni \u00e0 titre informatif uniquement et ne remplace pas l'avis d'un m\u00e9decin. La vitesse de s\u00e9dimentation est un test non sp\u00e9cifique qui doit toujours \u00eatre interpr\u00e9t\u00e9 dans le contexte clinique complet et en parall\u00e8le avec la CRP et les autres examens biologiques. Une VS normale n'exclut pas une maladie inflammatoire s\u00e9rieuse \u2014 notamment l'art\u00e9rite \u00e0 cellules g\u00e9antes dans 5 \u00e0 10 % des cas.<\/p>\n\n<\/div>\n<\/body>\n<\/html>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Vitesse de s\u00e9dimentation (VS) : valeurs normales, causes d’\u00e9l\u00e9vation et interpr\u00e9tation | Clinique Omicron<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"off","neve_meta_content_width":100,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"","_themeisle_gutenberg_block_has_review":false,"_metasync_otto_title":"S\u00e9dimentation VS | Brossard | Clinique Omicron","_metasync_otto_description":"S\u00e9dimentation VS S\u00e9dimentation VS est un test de laboratoire qui permet d'\u00e9valuer certains aspects de votre \u00e9tat de sant\u00e9. Ce test est disponible \u00e0 la Cliniq...","_metasync_otto_keywords":"","_metasync_otto_og_title":"Sedimentation Vs | Clinique Omicron Qu\u00e9bec","_metasync_otto_og_description":"S\u00e9dimentation VS S\u00e9dimentation VS est un test de laboratoire qui permet d'\u00e9valuer certains aspects de votre \u00e9tat de sant\u00e9. Ce test est disponible \u00e0 la Cliniq...","_metasync_otto_twitter_title":"Sedimentation Vs | Clinique Omicron","_metasync_otto_twitter_description":"S\u00e9dimentation VS S\u00e9dimentation VS est un test de laboratoire qui permet d'\u00e9valuer certains aspects de votre \u00e9tat de sant\u00e9. Ce test est disponible \u00e0 la Cliniq...","rank_math_title":"","rank_math_description":"","_yoast_wpseo_title":"","_yoast_wpseo_metadesc":"","_aioseo_title":"Vitesse de s\u00e9dimentation (VS) : valeurs normales, causes d'\u00e9l\u00e9vation et interpr\u00e9tation | Clinique Omicron","_aioseo_description":"La VS mesure indirectement l'inflammation par s\u00e9dimentation des GR. 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Erythrocytes sediment slowly under normal conditions, as their negative surface charge (zeta-potential - sialic acid) confers a mutual electrostatic repulsion that opposes aggregation. The SV is accelerated when high-molecular-weight plasma proteins - mainly fibrinogen (positive acute-phase reactant + increases in 24-48 h during inflammation) + immunoglobulins (IgG + IgA + IgM - increases in chronic infections + gammopathies + autoimmune diseases) + and the alpha-2 globulin fraction - adsorb to the surface of erythrocytes, reduce their zeta-potential and promote their aggregation into more rapidly sedimenting rolls. The VS is thus an indirect, non-specific marker of systemic inflammation - whose great strength lies in its sensitivity for detecting chronic inflammations (polymyalgia rheumatica + giant cell arteritis + myeloma + chronic infections) + and its great weakness in its lack of specificity (elevated in pregnancy + anemia + obesity + advanced age + acute infections + cancers + autoimmune diseases) and its slow response (rises in 24-48 h + remains elevated for weeks even after resolution of inflammation - unlike CRP, which normalizes in 3-5 days). The SV must always be interpreted in conjunction with the CRP and in the clinical context - the two markers are complementary, not redundant.\n <\/div>\n\n <h2>Valeurs normales selon l'\u00e2ge et le sexe<\/h2>\n <ul class=\"co-list\">\n <li><strong>Formule de Miller (estimation rapide des limites sup\u00e9rieures normales) :<\/strong> homme = \u00e2ge \/ 2 + femme = (\u00e2ge + 10) \/ 2 \u2192 exemples : homme 50 ans \u2192 VS < 25 mm\/h + femme 50 ans \u2192 VS < 30 mm\/h + homme 70 ans \u2192 VS < 35 mm\/h + femme 70 ans \u2192 VS < 40 mm\/h<\/li>\n <li><strong>Valeurs normales de r\u00e9f\u00e9rence usuelles :<\/strong> homme < 50 ans : < 15 mm\/h + homme > 50 ans : < 20 mm\/h + femme < 50 ans : < 20 mm\/h + femme > 50 ans : < 30 mm\/h + enfant : < 10\u201315 mm\/h<\/li>\n <li><strong>VS l\u00e9g\u00e8rement \u00e9lev\u00e9e (20\u201350 mm\/h) :<\/strong> variable clinical significance + can be physiological in the elderly + pregnant women + or pathological in many mild to moderate conditions<\/li>\n <li><strong>VS mod\u00e9r\u00e9ment \u00e9lev\u00e9e (50\u2013100 mm\/h) :<\/strong> significant + suggests active infection + chronic inflammatory disease + neoplasia<\/li>\n <li><strong>VS tr\u00e8s \u00e9lev\u00e9e (> 100 mm\/h) :<\/strong> clinically very important threshold value \u2192 90 % of cases have an identifiable serious cause \u2192 systematic in-depth workup \u2192 giant cell arteritis (GCA) ++ + multiple myeloma ++ + severe infections + severe autoimmune diseases + lymphomas<\/li>\n <\/ul>\n\n <h2>Causes d'\u00e9l\u00e9vation de la VS<\/h2>\n\n <table class=\"co-table\">\n <thead>\n <tr>\n <th>Category<\/th>\n <th>Main causes<\/th>\n <th>Mechanism and context<\/th>\n <\/tr>\n <\/thead>\n <tbody>\n <tr>\n <td>Inflammatory rheumatological diseases<\/td>\n <td>Art\u00e9rite \u00e0 cellules g\u00e9antes (ACG \u2014 art\u00e9rite temporale) ++ + polymyalgie rhumatismale (PMR) ++ + polyarthrite rhumato\u00efde + lupus + spondylarthrite axiale + vascularites + connectivites<\/td>\n <td>ACG et PMR : VS souvent > 50\u2013100 mm\/h + VS = crit\u00e8re diagnostique majeur de l'ACG + aussi crit\u00e8re de suivi du traitement par cortico\u00efdes (normalisation attendue sous traitement)<\/td>\n <\/tr>\n <tr>\n <td>Infections aigu\u00ebs et chroniques<\/td>\n <td>Infections bact\u00e9riennes s\u00e9v\u00e8res + endocardite infectieuse + ost\u00e9omy\u00e9lite + tuberculose + abc\u00e8s profonds + infections chroniques \u00e0 VIH + VHC + VHB<\/td>\n <td>Fibrinog\u00e8ne augmente en 24\u201348 h lors de l'infection \u2192 VS \u00e9lev\u00e9e + moins sensible que la CRP pour les infections aigu\u00ebs + mais utile pour les infections chroniques (tuberculose + endocardite)<\/td>\n <\/tr>\n <tr>\n <td>H\u00e9mopathies malignes<\/td>\n <td>My\u00e9lome multiple +++ (immunoglobulines monoclonales en tr\u00e8s grande quantit\u00e9) + macroglobulin\u00e9mie de Waldenstr\u00f6m + lymphomes<\/td>\n <td>My\u00e9lome : cause classique de VS tr\u00e8s \u00e9lev\u00e9e (> 100 mm\/h) par accumulation d'immunoglobulines monoclonales \u2192 \u00e9lectrophor\u00e8se des prot\u00e9ines s\u00e9riques syst\u00e9matique si VS inexpliqu\u00e9e > 100 mm\/h<\/td>\n <\/tr>\n <tr>\n <td>Solid cancers<\/td>\n <td>Cancer du rein + cancer du poumon + cancer colorectal + cancer gastrique + m\u00e9tastases + paran\u00e9oplasique<\/td>\n <td>\u00c9l\u00e9vation mod\u00e9r\u00e9e \u00e0 s\u00e9v\u00e8re + m\u00e9canisme : prot\u00e9ines de phase aigu\u00eb + n\u00e9crose + inflammation + doit \u00eatre \u00e9voqu\u00e9 si VS \u00e9lev\u00e9e sans autre explication \u00e9vidente + surtout apr\u00e8s 50 ans<\/td>\n <\/tr>\n <tr>\n <td>Physiological (non-pathological) causes<\/td>\n <td>Grossesse (2e\u20133e trimestre) + menstruation + \u00e2ge avanc\u00e9 + ob\u00e9sit\u00e9<\/td>\n <td>Grossesse : VS peut atteindre 40\u201370 mm\/h normalement (fibrinog\u00e8ne augmente physiologiquement) + grand \u00e2ge : VS tend \u00e0 augmenter avec l'\u00e2ge m\u00eame sans pathologie \u2192 utiliser la formule de Miller pour ajuster les normales<\/td>\n <\/tr>\n <tr>\n <td>Anemia<\/td>\n <td>Toute cause d'an\u00e9mie \u2192 VS augment\u00e9e par m\u00e9canisme physique<\/td>\n <td>Moins d'\u00e9rythrocytes \u2192 moins de r\u00e9pulsion \u2192 s\u00e9dimentation plus rapide \u2192 correction : la VS doit \u00eatre interpr\u00e9t\u00e9e en tenant compte de l'h\u00e9matocrite (h\u00e9matocrite bas = VS artificiellement \u00e9lev\u00e9e)<\/td>\n <\/tr>\n <tr>\n <td>Chronic renal failure<\/td>\n <td>IRC \u2192 accumulation de prot\u00e9ines inflammatoires + an\u00e9mie + hypoalbumin\u00e9mie<\/td>\n <td>VS souvent mod\u00e9r\u00e9ment \u00e9lev\u00e9e dans l'IRC \u2192 moins sp\u00e9cifique pour le diagnostic d'une inflammation surajout\u00e9e<\/td>\n <\/tr>\n <\/tbody>\n <\/table>\n\n <h2>Causes de VS basse ou normale malgr\u00e9 inflammation \u2014 faux n\u00e9gatifs<\/h2>\n <ul class=\"co-list\">\n <li><strong>Polyglobulin :<\/strong> very high hematocrit \u2192 RBCs are too numerous \u2192 repulsion between RBCs dominates \u2192 slowed sedimentation \u2192 falsely normal or low ESR even if inflammation is real<\/li>\n <li><strong>Cryoglobulin\u00e9mie + hypofibrinog\u00e9n\u00e9mie + CIVD :<\/strong> abnormal or reduced proteins \u2192 lowered VS<\/li>\n <li><strong>Dr\u00e9panocytose :<\/strong> Sickle RBCs do not stack in rolls \u2192 very low SV<\/li>\n <li><strong>Insuffisance cardiaque congestive s\u00e9v\u00e8re :<\/strong> hypervolemia \u2192 protein dilution \u2192 lowered VS<\/li>\n <li><strong>Active lupus :<\/strong> paradoxically, relapsing lupus may have a normal or low SV (immune complexes + cryoglobulins + fibrinogen consumption in associated DIC) \u2192 CRP is a better marker of lupus activity<\/li>\n <\/ul>\n\n <div class=\"co-infobox\">\n <span class=\"ico\">\u2119\ufe0f<\/span>\n <span>VS vs CRP \u2014 utilisation compl\u00e9mentaire : la CRP est un marqueur d'inflammation aigu\u00eb (monte en 6\u201312 h + se normalise en 3\u20135 jours + peu influenc\u00e9e par l'an\u00e9mie + la grossesse + l'\u00e2ge) tandis que la VS refl\u00e8te une inflammation chronique ou subaigu\u00eb (monte lentement en 24\u201348 h + reste \u00e9lev\u00e9e des semaines + tr\u00e8s influenc\u00e9e par l'an\u00e9mie + la grossesse + les immunoglobulines). Dans l'art\u00e9rite temporale et la PMR, les deux marqueurs sont \u00e9lev\u00e9s et utilis\u00e9s conjointement pour le diagnostic et le suivi. Dans le lupus, la CRP peut \u00eatre normale m\u00eame en pouss\u00e9e (sauf si infection bact\u00e9rienne) tandis que la VS est souvent \u00e9lev\u00e9e. Dans les infections aigu\u00ebs, la CRP est plus sensible et plus rapide que la VS.<\/span>\n <\/div>\n\n <h2>La VS dans l'art\u00e9rite \u00e0 cellules g\u00e9antes (ACG) \u2014 utilisation clinique cruciale<\/h2>\n <ul class=\"co-list\">\n <li><strong>Typical presentation:<\/strong> femme > 50 ans (pic 70\u201380 ans) + c\u00e9phal\u00e9es temporales + art\u00e8re temporale douloureuse et indur\u00e9e + claudication de la m\u00e2choire + troubles visuels (amaurose fugace \u2192 c\u00e9cit\u00e9 d\u00e9finitive si non trait\u00e9e) + polymyalgie rhumatismale associ\u00e9e dans 50 % des cas<\/li>\n <li><strong>VS dans l'ACG :<\/strong> VS > 50 mm\/h est un crit\u00e8re ACR majeur de l'ACG + VS > 100 mm\/h est tr\u00e8s \u00e9vocatrice + mais 5\u201310 % des ACG ont une VS normale \u2192 ne pas exclure le diagnostic sur une VS normale si forte suspicion clinique \u2192 biopsie de l'art\u00e8re temporale + \u00e9cho-Doppler des art\u00e8res temporales + PET-TDM<\/li>\n <li><strong>Urgent treatment (do not wait for biopsy):<\/strong> prednisone 60 mg\/day per os as soon as clinical suspicion arises \u2192 prevention of irreversible blindness \u2192 biopsy remains positive for 2-4 weeks on corticosteroids<\/li>\n <li><strong>Treatment follow-up :<\/strong> VS and CRP normalize on corticosteroids in 2-4 weeks \u2192 monthly monitoring to guide the decrease + a further rise suggests a relapse<\/li>\n <\/ul>\n\n <div class=\"co-urgence\">\n <div class=\"co-urgence-titre\">Urgent medical consultation<\/div>\n <p>Consulter un m\u00e9decin dans les 24 heures si une VS tr\u00e8s \u00e9lev\u00e9e (> 100 mm\/h) est d\u00e9couverte sans cause \u00e9vidente \u2014 ce r\u00e9sultat justifie un bilan approfondi (\u00e9lectrophor\u00e8se des prot\u00e9ines + NFS + CRP + bilan r\u00e9nal + h\u00e9patique + imagerie selon le contexte). Consulter en urgence imm\u00e9diate si la VS \u00e9lev\u00e9e s'accompagne de c\u00e9phal\u00e9es temporales + de troubles visuels + de claudication de la m\u00e2choire chez une personne de plus de 50 ans \u2014 ce tableau \u00e9voque une art\u00e9rite \u00e0 cellules g\u00e9antes, urgence ophtalmologique n\u00e9cessitant des cortico\u00efdes en urgence pour pr\u00e9venir la c\u00e9cit\u00e9. Pour la prescription et l'interpr\u00e9tation de la VS, Clinique Omicron offre des consultations dans ses points de service au Qu\u00e9bec et en t\u00e9l\u00e9m\u00e9decine. Pour prendre rendez-vous, visitez <a href=\"https:\/\/cliniqueomicron.ca\" style=\"color:#c0392b;font-weight:600;text-decoration:none;\">cliniqueomicron.ca<\/a>.<\/p>\n <\/div>\n\n <h2>Consult at Clinique Omicron<\/h2>\n <p>Les m\u00e9decins et infirmiers praticiens sp\u00e9cialis\u00e9s (IPS) de Clinique Omicron prescrivent et interpr\u00e8tent la VS dans son contexte clinique en l'associant \u00e0 la CRP, \u00e0 la NFS et aux autres marqueurs inflammatoires, distinguent les causes physiologiques des causes pathologiques d'\u00e9l\u00e9vation, prescrivent le bilan d'investigation appropri\u00e9 selon le niveau de VS et les signes cliniques associ\u00e9s, initient les cortico\u00efdes en urgence si une art\u00e9rite \u00e0 cellules g\u00e9antes est suspect\u00e9e, et orientent vers la rhumatologie + l'h\u00e9matologie ou l'oncologie selon l'\u00e9tiologie identifi\u00e9e. Des consultations sont disponibles dans plusieurs points de service au Qu\u00e9bec et en t\u00e9l\u00e9m\u00e9decine. Pour prendre rendez-vous, visitez <a href=\"https:\/\/cliniqueomicron.ca\" style=\"color:#4D6577;font-weight:600;text-decoration:none;\">cliniqueomicron.ca<\/a>.<\/p>\n\n <p class=\"co-disclaimer\">Le contenu de cette page est fourni \u00e0 titre informatif uniquement et ne remplace pas l'avis d'un m\u00e9decin. La vitesse de s\u00e9dimentation est un test non sp\u00e9cifique qui doit toujours \u00eatre interpr\u00e9t\u00e9 dans le contexte clinique complet et en parall\u00e8le avec la CRP et les autres examens biologiques. Une VS normale n'exclut pas une maladie inflammatoire s\u00e9rieuse \u2014 notamment l'art\u00e9rite \u00e0 cellules g\u00e9antes dans 5 \u00e0 10 % des cas.<\/p>\n\n<\/div>\n<\/body>\n<\/html>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Vitesse de s\u00e9dimentation (VS) : valeurs normales, causes d’\u00e9l\u00e9vation et interpr\u00e9tation | Clinique Omicron<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"off","neve_meta_content_width":100,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"","_themeisle_gutenberg_block_has_review":false,"_metasync_otto_title":"S\u00e9dimentation VS | Brossard | Clinique Omicron","_metasync_otto_description":"S\u00e9dimentation VS S\u00e9dimentation VS est un test de laboratoire qui permet d'\u00e9valuer certains aspects de votre \u00e9tat de sant\u00e9. Ce test est disponible \u00e0 la Cliniq...","_metasync_otto_keywords":"","_metasync_otto_og_title":"Sedimentation Vs | Clinique Omicron Qu\u00e9bec","_metasync_otto_og_description":"S\u00e9dimentation VS S\u00e9dimentation VS est un test de laboratoire qui permet d'\u00e9valuer certains aspects de votre \u00e9tat de sant\u00e9. Ce test est disponible \u00e0 la Cliniq...","_metasync_otto_twitter_title":"Sedimentation Vs | Clinique Omicron","_metasync_otto_twitter_description":"S\u00e9dimentation VS S\u00e9dimentation VS est un test de laboratoire qui permet d'\u00e9valuer certains aspects de votre \u00e9tat de sant\u00e9. Ce test est disponible \u00e0 la Cliniq...","rank_math_title":"","rank_math_description":"","_yoast_wpseo_title":"","_yoast_wpseo_metadesc":"","_aioseo_title":"Vitesse de s\u00e9dimentation (VS) : valeurs normales, causes d'\u00e9l\u00e9vation et interpr\u00e9tation | Clinique Omicron","_aioseo_description":"La VS mesure indirectement l'inflammation par s\u00e9dimentation des GR. Formule Miller \u00e2ge\/2, VS >100mm\/h my\u00e9lome art\u00e9rite temporale ACG urgence cortico\u00efdes, VS normale CRP \u00e9lev\u00e9e diff\u00e9rences compl\u00e9mentarit\u00e9 au Qu\u00e9bec.","_metasync_seo_title":"","_metasync_seo_desc":"","_metasync_breadcrumb_title":"","_metasync_primary_category":0,"_metasync_primary_product_cat":0,"_metasync_otto_disabled":"","_metasync_hreflang":"","_metasync_plugin_sync_ts":"{\"aioseo\":\"2026-05-10T07:42:19+00:00\"}","_metasync_robots_advanced":"","footnotes":""},"class_list":["post-24956","page","type-page","status-publish","hentry"],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t<meta name=\"description\" content=\"S\u00e9dimentation VS S\u00e9dimentation VS est un test de laboratoire qui permet d'\u00e9valuer certains aspects de votre \u00e9tat de sant\u00e9. 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