Thrombocytopenia: Causes, Diagnosis, and Treatment of Platelet Deficiency | Clinique Omicron<\/title>\n<meta name=\"description\" content=\"La thrombocytop\u00e9nie est une r\u00e9duction des plaquettes sous 150 000\/\u00b5L causant un risque h\u00e9morragique. PTI, TIH, CIVD, m\u00e9dicaments, frottis plaquettes et prise en charge au Qu\u00e9bec.\">\n<meta name=\"keywords\" content=\"thrombocytop\u00e9nie, plaquettes basses, PTI purpura thrombop\u00e9nique idiopathique, TIH thrombocytop\u00e9nie h\u00e9parine, thrombocytop\u00e9nie m\u00e9dicamenteuse, CIVD thrombocytop\u00e9nie, thrombocytop\u00e9nie traitement, thrombocytop\u00e9nie causes, frottis plaquettes, thrombocytop\u00e9nie Qu\u00e9bec\">\n<link rel=\"preconnect\" href=\"https:\/\/fonts.googleapis.com\">\n<link href=\"https:\/\/fonts.googleapis.com\/css2?family=Cinzel:wght@600&family=Poppins:wght@400;500;600;700&display=swap\" rel=\"stylesheet\">\n<style>\n@import url('https:\/\/fonts.googleapis.com\/css2?family=Cinzel:wght@600&family=Poppins:wght@400;500;600;700&display=swap');\n\n.co-wrap * {\n font-family: 'Poppins', sans-serif;\n box-sizing: border-box;\n}\n.co-wrap {\n max-width: 1100px;\n margin: 0 auto;\n padding: 30px 0 60px;\n margin-top: 10px;\n}\n.co-label {\n font-family: 'Cinzel', serif;\n font-size: 14px;\n font-weight: bold;\n letter-spacing: 1px;\n text-transform: uppercase;\n color: #4D6577;\n margin-bottom: 14px;\n display: block;\n}\n.co-wrap h1 {\n font-size: 32px;\n font-weight: 500;\n color: #323C52;\n margin: 0 0 22px;\n line-height: 1.2;\n letter-spacing: 0.5px;\n}\n.co-intro {\n font-size: 16px;\n font-weight: 400;\n line-height: 1.75;\n color: #4D6577;\n margin-bottom: 36px;\n padding-bottom: 32px;\n border-bottom: 1px solid rgba(77,101,119,.2);\n}\n.co-wrap h2 {\n font-size: 20px;\n font-weight: 600;\n color: #323C52;\n margin: 32px 0 12px;\n letter-spacing: 0.3px;\n}\n.co-wrap p {\n font-size: 15px;\n font-weight: 400;\n color: #4D6577;\n line-height: 1.7;\n margin-bottom: 14px;\n}\n.co-list {\n list-style: none;\n padding: 0;\n margin: 12px 0 24px;\n}\n.co-list li {\n font-size: 15px;\n font-weight: 400;\n color: #4D6577;\n padding: 10px 14px 10px 38px;\n margin-bottom: 8px;\n border-radius: 6px;\n position: relative;\n background: rgba(77,101,119,.06);\n border-left: 3px solid #4D6577;\n}\n.co-list li::before {\n content: \"\u2713\";\n position: absolute;\n left: 12px;\n font-weight: 700;\n color: #4D6577;\n}\n.co-table {\n width: 100%;\n border-collapse: collapse;\n margin: 14px 0 22px;\n font-size: 14px;\n border-radius: 8px;\n overflow: hidden;\n}\n.co-table thead tr {\n background: #323C52;\n color: #fff;\n}\n.co-table thead th {\n padding: 11px 16px;\n text-align: left;\n font-weight: 600;\n font-size: 13px;\n}\n.co-table tbody tr:nth-child(even) {\n background: rgba(77,101,119,.06);\n}\n.co-table tbody tr:nth-child(odd) {\n background: #fff;\n}\n.co-table td {\n padding: 10px 16px;\n color: #4D6577;\n border-bottom: 1px solid rgba(77,101,119,.12);\n font-size: 14px;\n vertical-align: top;\n}\n.co-table td:first-child {\n font-weight: 600;\n color: #323C52;\n}\n.co-infobox {\n display: flex;\n gap: 12px;\n background: rgba(77,101,119,.06);\n border-radius: 8px;\n border-left: 4px solid #4D6577;\n padding: 14px 18px;\n margin: 18px 0 28px;\n font-size: 14px;\n font-weight: 400;\n color: #4D6577;\n line-height: 1.65;\n}\n.co-infobox .ico {\n font-size: 18px;\n flex-shrink: 0;\n}\n.co-urgence {\n background: #fff8f8;\n border-left: 5px solid #c0392b;\n border-radius: 6px;\n padding: 20px 26px;\n margin: 24px 0 32px;\n}\n.co-urgence .co-urgence-titre {\n font-size: 13px;\n font-weight: 700;\n color: #c0392b;\n letter-spacing: 1.5px;\n text-transform: uppercase;\n margin-bottom: 10px;\n}\n.co-urgence p {\n color: #5a2020;\n font-size: 14px;\n margin: 0 0 10px;\n line-height: 1.7;\n}\n.co-urgence p:last-child {\n margin-bottom: 0;\n}\n.co-disclaimer {\n font-size: 13px;\n color: #8a9aaa;\n font-style: italic;\n border-top: 1px solid rgba(77,101,119,.15);\n padding-top: 24px;\n margin-top: 40px;\n line-height: 1.6;\n}\n<\/style>\n<\/head>\n<body>\n<div class=\"co-wrap\">\n\n <span class=\"co-label\">Hematology & Internal Medicine & Family Medicine<\/span>\n <h1>Thrombocytop\u00e9nie<\/h1>\n<style>.oc-fiche-cta{margin:8px 0 34px;padding:22px 24px;border:1.5px solid rgba(50,60,82,.15);border-left:4px solid #FF611C;border-radius:12px;background:#F4F6F8;font-family:Poppins,sans-serif}.oc-fiche-cta-t{font-size:18px;font-weight:600;color:#323C52;margin:0 0 4px;line-height:1.35}.oc-fiche-cta-x{font-size:15px;color:#4D6577;margin:0 0 14px;line-height:1.55}.oc-fiche-cta-b{display:flex;flex-wrap:wrap;gap:10px}.oc-fiche-cta-b a{display:inline-flex;align-items:center;justify-content:center;min-height:44px;padding:10px 18px;border-radius:8px;font-size:14px;font-weight:600;text-decoration:none;box-sizing:border-box}.oc-fiche-cta-b .oc-p{background:#FF611C;color:#fff}.oc-fiche-cta-b .oc-p:hover{background:#E04E0C}.oc-fiche-cta-b .oc-s{background:#fff;color:#323C52;border:1.5px solid rgba(50,60,82,.25)}@media (max-width:600px){.co-wrap h1{font-size:24px;line-height:1.25;text-transform:none}.oc-fiche-cta{padding:18px 16px}.oc-fiche-cta-b a{flex:1 1 100%}body .co-wrap > .co-table,body .co-wrap > .co-table tbody,body .co-wrap > .co-table tr,body .co-wrap > .co-table td{display:block;width:100%;box-sizing:border-box}body .co-wrap > .co-table{min-width:0;table-layout:auto}body .co-wrap > .co-table thead{display:none}body .co-wrap > .co-table tr{margin:0 0 10px;border:1px solid rgba(77,101,119,.18);border-radius:8px;overflow:hidden}body .co-wrap > .co-table td{padding:9px 12px;border:0}body .co-wrap > .co-table td:first-child{font-weight:600;color:#323C52;background:rgba(77,101,119,.07)}#ocw{transform:scale(.8);transform-origin:bottom right}}<\/style><div class=\"oc-fiche-cta\" data-oc-cta=\"fiche-haut-consult\"><p class=\"oc-fiche-cta-t\">Obtenir un avis adapt\u00e9 \u00e0 votre situation<\/p><p class=\"oc-fiche-cta-x\">Consultation en clinique ou en t\u00e9l\u00e9consultation, partout au Qu\u00e9bec.<\/p><div class=\"oc-fiche-cta-b\"><a class=\"oc-p\" href=\"https:\/\/cliniqueomicron.ca\/rendez-vous\/\">Make an appointment<\/a><a class=\"oc-s\" href=\"https:\/\/cliniqueomicron.ca\/consultation-en-ligne\/\">Consult online<\/a><a class=\"oc-s\" href=\"tel:+15146063350\">514 606-3350<\/a><\/div><\/div>\n\n\n <div class=\"co-intro\">\n La thrombocytop\u00e9nie (ou thrombop\u00e9nie) est d\u00e9finie par une num\u00e9ration plaquettaire inf\u00e9rieure \u00e0 150 000 plaquettes par microlitre (\u00b5L) de sang \u2014 la valeur normale \u00e9tant de 150 000\u2013400 000\/\u00b5L \u2014 r\u00e9sultant soit d'une production insuffisante de plaquettes dans la moelle osseuse + soit d'une destruction acc\u00e9l\u00e9r\u00e9e des plaquettes en p\u00e9riph\u00e9rie (immunologique + m\u00e9canique + consommation) + soit d'une s\u00e9questration excessive dans la rate (hyperspl\u00e9nisme) + soit d'une dilution dans un contexte de transfusions massives. La gravit\u00e9 clinique de la thrombocytop\u00e9nie est directement corr\u00e9l\u00e9e au chiffre de plaquettes : thrombocytop\u00e9nie l\u00e9g\u00e8re (100 000\u2013150 000\/\u00b5L) \u2192 risque h\u00e9morragique minimal + g\u00e9n\u00e9ralement asymptomatique + thrombocytop\u00e9nie mod\u00e9r\u00e9e (50 000\u2013100 000\/\u00b5L) \u2192 saignements possibles lors de traumatismes ou de chirurgies + thrombocytop\u00e9nie s\u00e9v\u00e8re (20 000\u201350 000\/\u00b5L) \u2192 risque h\u00e9morragique spontan\u00e9 + purpura + \u00e9pistaxis + m\u00e9norragies + thrombocytop\u00e9nie tr\u00e8s s\u00e9v\u00e8re (<20 000\/\u00b5L) \u2192 risque d'h\u00e9morragie c\u00e9r\u00e9brale spontan\u00e9e + h\u00e9morragie visc\u00e9rale + urgence m\u00e9dicale. Le frottis sanguin est l'examen fondamental initial : il permet de confirmer la thrombocytop\u00e9nie (exclure la pseudothrombocytop\u00e9nie sur EDTA) + d'\u00e9valuer la morphologie des plaquettes (macroplaquettes = production acc\u00e9l\u00e9r\u00e9e + microplaquettes = syndrome de Wiskott-Aldrich) + et de rechercher des anomalies associ\u00e9es des autres lign\u00e9es (schizocytes \u2192 MAT + blastes \u2192 leuc\u00e9mie + corps de D\u00f6hle + granulations toxiques \u2192 sepsis) qui orientent le diagnostic \u00e9tiologique.\n <\/div>\n\n <h2>D\u00e9marche diagnostique initiale<\/h2>\n <ul class=\"co-list\">\n <li><strong>Confirmer la thrombocytop\u00e9nie \u2014 exclure la pseudothrombocytop\u00e9nie :<\/strong> Repeat NFS on citrate (blue) tube or on heparin tube \u2192 if platelets normal = pseudothrombocytopenia on EDTA (artefactual platelet agglutination in the presence of EDTA by EDTA-dependent anti-platelet antibodies \u2192 falsely low on the analyzer) \u2192 frequent (0.1\u20130.3 % of the population) + benign + without clinical significance<\/li>\n <li><strong>Manual blood smear:<\/strong> confirm thrombocytopenia + evaluate platelet size + look for aggregates (clumping) + schistocytes (MAT) + blasts (acute leukemia) + atypical lymphocytes (EBV) + D\u00f6hle bodies (infection)<\/li>\n <li><strong>Anamn\u00e8se cibl\u00e9e :<\/strong> Medications (ALL medications + including over-the-counter medications + supplements + and recently discontinued medications) + alcohol + recent infections + history of bleeding + family history + pregnancy + recent transfusions + HIV + Hepatitis C + Lupus + recent surgery + hemodialysis<\/li>\n <li><strong>Physical examination :<\/strong> purpura (petechiae + ecchymoses) + splenomegaly (hypersplenism + portal hypertension + lymphoma) + lymphadenopathy (lymphoma) + signs of chronic liver disease + signs of SLE (malar rash) + signs of sepsis<\/li>\n <\/ul>\n\n <h2>Causes de thrombocytop\u00e9nie par m\u00e9canisme<\/h2>\n\n <table class=\"co-table\">\n <thead>\n <tr>\n <th>Mechanism<\/th>\n <th>Main causes<\/th>\n <th>\u00c9l\u00e9ments orientants<\/th>\n <\/tr>\n <\/thead>\n <tbody>\n <tr>\n <td>Destruction immune (anti-platelet antibodies)<\/td>\n <td>PTI (purpura thrombop\u00e9nique immunologique) + TIH (thrombocytop\u00e9nie induite par l'h\u00e9parine) + thrombocytop\u00e9nie m\u00e9dicamenteuse (quinine + vancomycine + lin\u00e9zolide + c\u00e9phalosporines + etc.) + lupus + VIH + VHC + grossesse (HELLP + thrombocytop\u00e9nie gestationnelle)<\/td>\n <td>Moelle osseuse riche en m\u00e9gacaryocytes (production compensatrice acc\u00e9l\u00e9r\u00e9e) + macroplaquettes au frottis + Coombs pour anti-plaquettes (test de Dixon) + anticorps anti-plaquettes + bilan auto-immun<\/td>\n <\/tr>\n <tr>\n <td>Thrombotic Microangiopathy (TMA)<\/td>\n <td>PTT (purpura thrombotique thrombocytop\u00e9nique) + SHU + HELLP + CIVD + HTA maligne + MAT m\u00e9dicamenteuse<\/td>\n <td>Schizocytes +++ au frottis + Coombs n\u00e9gatif + LDH \u00e9lev\u00e9e + haptoglobine effondr\u00e9e + cr\u00e9atinine \u00e9lev\u00e9e + ADAMTS13 < 10 % si PTT \u2192 traitement par \u00e9changes plasmatiques en urgence<\/td>\n <\/tr>\n <tr>\n <td>Consumption (CIVD)<\/td>\n <td>Sepsis + trauma s\u00e9v\u00e8re + cancer + br\u00fblures + embolie amniotique + HELLP<\/td>\n <td>TP allong\u00e9 + APTT allong\u00e9 + fibrinog\u00e8ne bas + D-dim\u00e8res tr\u00e8s \u00e9lev\u00e9s + schizocytes possibles + contexte de choc ou infection s\u00e9v\u00e8re<\/td>\n <\/tr>\n <tr>\n <td>Insufficient production (power plants)<\/td>\n <td>Aplasie m\u00e9dullaire + leuc\u00e9mie aigu\u00eb + SMD (syndrome my\u00e9lodysplasique) + chimioth\u00e9rapie + radioth\u00e9rapie + envahissement m\u00e9dullaire (m\u00e9tastases + lymphome) + carence B12\/folates + alcoolisme (toxicit\u00e9 directe sur la moelle) + infection virale (VIH + EBV + CMV + parvovirus B19)<\/td>\n <td>Bi- ou pancytop\u00e9nie + microplaquettes ou plaquettes normales (pas de macroplaquettes) + my\u00e9logramme\/biopsie ost\u00e9om\u00e9dullaire + LDH \u00e9lev\u00e9e si h\u00e9mopathie maligne<\/td>\n <\/tr>\n <tr>\n <td>S\u00e9questration spl\u00e9nique<\/td>\n <td>Hypertension portale (cirrhose) + spl\u00e9nom\u00e9galie congestive + lymphome + sarco\u00efdose + leishmaniose<\/td>\n <td>Spl\u00e9nom\u00e9galie \u00e0 l'\u00e9chographie + thrombocytop\u00e9nie mod\u00e9r\u00e9e (40 000\u2013100 000\/\u00b5L) + souvent pancytop\u00e9nie + signes de cirrhose ou de maladie de base<\/td>\n <\/tr>\n <\/tbody>\n <\/table>\n\n <h2>PTI (Purpura Thrombop\u00e9nique Immunologique) \u2014 d\u00e9tails<\/h2>\n <ul class=\"co-list\">\n <li><strong>Definition:<\/strong> Immune thrombocytopenia + anti-platelet autoantibodies (anti-GPIIb-IIIa + anti-GPIb) + in the absence of other identifiable causes + diagnosis of exclusion<\/li>\n <li><strong>Shapes<\/strong> PTI aigu (enfant + souvent post-viral + gu\u00e9rison spontan\u00e9e dans 80\u201390 % en 6 mois) + PTI chronique (adulte + femme jeune ++ + persiste > 12 mois) + PTI secondaire (lupus + VIH + VHC + m\u00e9dicaments)<\/li>\n <li><strong>Balance<\/strong> NFS + Pap smear + group + RAI + HIV serology + HCV + autoimmune workup (ANA) + H. pylori (to be treated if positive \u2192 possible resolution of ITP) + in children: no bone marrow aspiration if typical presentation<\/li>\n <li><strong>Treatment (adult):<\/strong> plaquettes > 30 000 sans saignement \u2192 surveillance + plaquettes < 30 000 + ou saignements : cortico\u00efdes (prednisone 1 mg\/kg\/j \u00d7 4 semaines) + ou dexam\u00e9thasone 40 mg\/j \u00d7 4 jours (r\u00e9ponse plus rapide) + IgIV 1 g\/kg\/j \u00d7 1\u20132 jours (urgence + pr\u00e9-op\u00e9ratoire) + si r\u00e9fractaire : rituximab (375 mg\/m\u00b2 \u00d7 4 semaines) + eltrombopag + avatrombopag + romiplostim (agonistes du r\u00e9cepteur de la thrombopo\u00ef\u00e9tine) + spl\u00e9nectomie (r\u00e9mission 60\u201370 % \u00e0 long terme)<\/li>\n <\/ul>\n\n <h2>TIH (Thrombocytop\u00e9nie Induite par l'H\u00e9parine) \u2014 urgence m\u00e9dicale<\/h2>\n <ul class=\"co-list\">\n <li><strong>M\u00e9canisme :<\/strong> IgG antibodies anti-heparin-PF4 (platelet factor 4) complex \u2192 platelet activation \u2192 thrombocytopenia + paradoxical thromboses (venous + arterial) \u2192 HIT = PROthrombotic thrombocytopenia (the risk is not bleeding but thrombosis)<\/li>\n <li><strong>Crit\u00e8res cliniques \u2014 score 4T :<\/strong> Thrombocytop\u00e9nie (chute > 50 % ou nadir 20 000\u2013100 000) + Timing (chute J5\u2013J10 sous h\u00e9parine + ou < J1 si exposition r\u00e9cente) + Thrombose (nouvelle thrombose + ou n\u00e9crose cutan\u00e9e au site d'injection) + autres causes de Thrombocytop\u00e9nie absentes \u2192 score 0\u20138 : 0\u20133 = probabilit\u00e9 faible + 4\u20135 = interm\u00e9diaire + 6\u20138 = \u00e9lev\u00e9e<\/li>\n <li><strong>Conduite \u00e0 tenir si TIH suspect\u00e9e :<\/strong> IMMEDIATELY STOP all heparin (UFH + LMWH + heparinized catheter) + DO NOT transfuse platelets (worsens thrombosis) + SUBSTITUTE with non-heparin anticoagulant \u2192 argatroban (IV) + fondaparinux (SC) + bivalirudin + danaparoid + anti-PF4\/heparin serology (ELISA) + platelet activation test (HIPA)<\/li>\n <li><strong>Warfarin in the treatment of VTE:<\/strong> DO NOT initiate warfarin during the acute phase (risk of skin necrosis + limb gangrene due to protein C drop before sufficient anticoagulation).<\/li>\n <\/ul>\n\n <div class=\"co-infobox\">\n <span class=\"ico\">\u2119\ufe0f<\/span>\n <span>La thrombocytop\u00e9nie induite par l'h\u00e9parine (TIH) est un paradoxe clinique essentiel : c'est une thrombocytop\u00e9nie PROTHROMBOTIQUE et non h\u00e9morragique. Arr\u00eater l'h\u00e9parine imm\u00e9diatement d\u00e8s la suspicion + NE JAMAIS transfuser des plaquettes (risque d'aggraver les thromboses \u2014 les plaquettes sont du carburant pour les thrombi dans la TIH) + substituer imm\u00e9diatement par un anticoagulant non h\u00e9parinique. Une thrombose (TVP + EP + art\u00e9rielle + CIVD) dans les 5 \u00e0 10 jours suivant le d\u00e9but d'une h\u00e9parine doit faire syst\u00e9matiquement \u00e9voquer une TIH.<\/span>\n <\/div>\n\n <h2>Platelet transfusion thresholds<\/h2>\n <ul class=\"co-list\">\n <li><strong>Plaquettes < 10 000\/\u00b5L :<\/strong> prophylactic transfusion in the absence of bleeding (prevention of spontaneous intracranial hemorrhage)<\/li>\n <li><strong>Plaquettes < 20 000\/\u00b5L + fi\u00e8vre + coagulopathie :<\/strong> prophylactic transfusion<\/li>\n <li><strong>Plaquettes < 50 000\/\u00b5L + geste invasif pr\u00e9vu (ponction lombaire + endoscopie avec biopsie + chirurgie mineure) :<\/strong> Pre-procedure transfusion<\/li>\n <li><strong>Plaquettes < 100 000\/\u00b5L + neurochirurgie + chirurgie ophtalmique :<\/strong> Preoperative transfusion<\/li>\n <li><strong>Contre-indications absolues \u00e0 la transfusion de plaquettes :<\/strong> PTT + TIH + SHU \u2192 worsening of microvascular thrombosis<\/li>\n <\/ul>\n\n <div class=\"co-urgence\">\n <div class=\"co-urgence-titre\">Medical emergencies<\/div>\n <p>Se rendre imm\u00e9diatement aux urgences si une thrombocytop\u00e9nie s\u00e9v\u00e8re (< 20 000\/\u00b5L) est d\u00e9couverte + ou si des saignements spontan\u00e9s (p\u00e9t\u00e9chies diffuses + h\u00e9morragie nasale ou buccale incoercible + sang dans les urines ou les selles) apparaissent + ou si une chute brutale des plaquettes survient chez un patient sous h\u00e9parine (\u00e9voquer une TIH \u2014 arr\u00eater imm\u00e9diatement l'h\u00e9parine). Pour le bilan initial d'une thrombocytop\u00e9nie l\u00e9g\u00e8re \u00e0 mod\u00e9r\u00e9e d\u00e9couverte fortuitement et l'orientation vers l'h\u00e9matologie, Clinique Omicron offre des consultations m\u00e9dicales dans ses points de service au Qu\u00e9bec et en t\u00e9l\u00e9m\u00e9decine. Pour prendre rendez-vous, visitez <a href=\"https:\/\/cliniqueomicron.ca\" style=\"color:#c0392b;font-weight:600;text-decoration:none;\">cliniqueomicron.ca<\/a>.<\/p>\n <\/div>\n\n <h2>Consult at Clinique Omicron<\/h2>\n <p>Les m\u00e9decins et infirmiers praticiens sp\u00e9cialis\u00e9s (IPS) de Clinique Omicron confirment la thrombocytop\u00e9nie par le frottis sanguin (exclure la pseudothrombocytop\u00e9nie sur EDTA), prescrivent le bilan \u00e9tiologique orient\u00e9 (s\u00e9rologie VIH + VHC + bilan auto-immun + bilan de MAT si schizocytes), identifient les m\u00e9dicaments causaux (TIH + thrombocytop\u00e9nie m\u00e9dicamenteuse), initient la prednisone pour le PTI, orientent en urgence vers l'h\u00e9matologie pour les thrombocytop\u00e9nies s\u00e9v\u00e8res ou les MAT (PTT \u2192 \u00e9changes plasmatiques en urgence), et assurent le suivi des PTI chroniques. Des consultations sont disponibles dans plusieurs points de service au Qu\u00e9bec et en t\u00e9l\u00e9m\u00e9decine. Pour prendre rendez-vous, visitez <a href=\"https:\/\/cliniqueomicron.ca\" style=\"color:#4D6577;font-weight:600;text-decoration:none;\">cliniqueomicron.ca<\/a>.<\/p>\n\n <p class=\"co-disclaimer\">Le contenu de cette page est fourni \u00e0 titre informatif uniquement et ne remplace pas l'avis d'un m\u00e9decin ou d'un h\u00e9matologue. La thrombocytop\u00e9nie induite par l'h\u00e9parine (TIH) est une urgence m\u00e9dicale \u2014 arr\u00eater l'h\u00e9parine imm\u00e9diatement et NE PAS transfuser des plaquettes. Un PTT (purpura thrombotique thrombocytop\u00e9nique) avec ADAMTS13 < 10 % n\u00e9cessite des \u00e9changes plasmatiques en urgence absolue.<\/p>\n\n<\/div>\n<\/body>\n<\/html>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Thrombocytop\u00e9nie : causes, diagnostic et traitement du d\u00e9ficit plaquettaire | Clinique Omicron H\u00e9matologie & M\u00e9decine interne & M\u00e9decine de famille Thrombocytop\u00e9nie La thrombocytop\u00e9nie (ou thrombop\u00e9nie) est d\u00e9finie par une num\u00e9ration plaquettaire inf\u00e9rieure \u00e0 150 000 plaquettes par microlitre (\u00b5L) de sang \u2014 la valeur normale \u00e9tant de 150 000\u2013400 000\/\u00b5L \u2014 r\u00e9sultant soit d’une production… <a href=\"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/\" rel=\"bookmark\">Read More \"<span class=\"screen-reader-text\">Thrombocytopenia: Causes, Diagnosis, and Treatment of Platelet Deficiency | Clinique Omicron<\/span><\/a><\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"off","neve_meta_content_width":100,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"","_themeisle_gutenberg_block_has_review":false,"_metasync_otto_title":"Thrombocytop\u00e9nie | Brossard | Clinique Omicron","_metasync_otto_description":"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...","_metasync_otto_keywords":"","_metasync_otto_og_title":"Thrombocytopenie | Clinique Omicron Qu\u00e9bec","_metasync_otto_og_description":"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...","_metasync_otto_twitter_title":"Thrombocytopenie | Clinique Omicron","_metasync_otto_twitter_description":"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...","rank_math_title":"","rank_math_description":"","_yoast_wpseo_title":"","_yoast_wpseo_metadesc":"","_aioseo_title":"Thrombocytop\u00e9nie : causes, diagnostic et traitement du d\u00e9ficit plaquettaire | Clinique Omicron","_aioseo_description":"La thrombocytop\u00e9nie est une r\u00e9duction des plaquettes <150 000\/\u00b5L. PTI prednisone rituximab eltrombopag, TIH arr\u00eater h\u00e9parine NE PAS transfuser anti-FP4, schizocytes PTT \u00e9changes plasmatiques urgence, frottis EDTA au Qu\u00e9bec.","_metasync_seo_title":"Thrombocytop\u00e9nie | Clinique Omicron","_metasync_seo_desc":"","_metasync_breadcrumb_title":"","_metasync_primary_category":0,"_metasync_primary_product_cat":0,"_metasync_imported_seo_title":"","_metasync_imported_seo_desc":"","_metasync_otto_disabled":"","_metasync_hreflang":"","_metasync_plugin_sync_ts":"{\"aioseo\":\"2026-09-03T07:53:13+00:00\"}","_metasync_robots_advanced":"","_metasync_og_title":"Thrombocytopenie | Clinique Omicron Qu\u00e9bec","_metasync_og_description":"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...","_metasync_twitter_title":"Thrombocytopenie | Clinique Omicron","_metasync_twitter_description":"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...","footnotes":""},"class_list":["post-25006","page","type-page","status-publish","hentry"],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t<meta name=\"description\" content=\"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...\" \/>\n\t<meta name=\"robots\" content=\"max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n\t<meta name=\"google-site-verification\" content=\"yYDMZv-nme7Cg-KrW5GmEWceBTrCDv8zhSkkXdJSnyM\" \/>\n\t<meta name=\"msvalidate.01\" content=\"3225E6935FC4F40C7DDCE56C37141BA8\" \/>\n\t<link rel=\"canonical\" href=\"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO Pro (AIOSEO) 5.0.1.1\" \/>\n\t\t<meta property=\"og:locale\" content=\"en_US\" \/>\n\t\t<meta property=\"og:site_name\" content=\"Clinique Omicron - Clinique M\u00e9dicale\" \/>\n\t\t<meta property=\"og:type\" content=\"article\" \/>\n\t\t<meta property=\"og:title\" content=\"Thrombocytopenie | Clinique Omicron Qu\u00e9bec\" \/>\n\t\t<meta property=\"og:description\" content=\"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...\" \/>\n\t\t<meta property=\"og:url\" content=\"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/\" \/>\n\t\t<meta property=\"og:image\" content=\"https:\/\/cliniqueomicron.ca\/wp-content\/uploads\/2025\/12\/unnamed-1-e1765579964732.jpg\" \/>\n\t\t<meta property=\"og:image:secure_url\" content=\"https:\/\/cliniqueomicron.ca\/wp-content\/uploads\/2025\/12\/unnamed-1-e1765579964732.jpg\" \/>\n\t\t<meta property=\"article:published_time\" content=\"2026-03-01T02:54:46+00:00\" \/>\n\t\t<meta property=\"article:modified_time\" content=\"2026-09-14T23:50:55+00:00\" \/>\n\t\t<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/cliniqueomicron\" \/>\n\t\t<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n\t\t<meta name=\"twitter:site\" content=\"@CliniqueOmicron\" \/>\n\t\t<meta name=\"twitter:title\" content=\"Thrombocytopenie | Clinique Omicron Qu\u00e9bec\" \/>\n\t\t<meta name=\"twitter:description\" content=\"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...\" \/>\n\t\t<meta name=\"twitter:creator\" content=\"@CliniqueOmicron\" \/>\n\t\t<meta name=\"twitter:image\" content=\"https:\/\/cliniqueomicron.ca\/wp-content\/uploads\/2025\/12\/unnamed-1-e1765579964732.jpg\" \/>\n\t\t<script type=\"application\/ld+json\" class=\"aioseo-schema\">\n\t\t\t{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en\\\/thrombocytopenie\\\/#breadcrumblist\",\"itemListElement\":[{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en#listItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en\",\"nextItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en\\\/thrombocytopenie\\\/#listItem\",\"name\":\"Thrombocytop\\u00e9nie : causes, diagnostic et traitement du d\\u00e9ficit plaquettaire | Clinique Omicron\"}},{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en\\\/thrombocytopenie\\\/#listItem\",\"position\":2,\"name\":\"Thrombocytop\\u00e9nie : causes, diagnostic et traitement du d\\u00e9ficit plaquettaire | Clinique Omicron\",\"previousItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en#listItem\",\"name\":\"Accueil\"}}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en\\\/thrombocytopenie\\\/#webpage\",\"url\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en\\\/thrombocytopenie\\\/\",\"name\":\"Thrombocytop\\u00e9nie | Clinique Omicron\",\"description\":\"Thrombocytop\\u00e9nie Thrombocytop\\u00e9nie est une condition m\\u00e9dicale qui peut n\\u00e9cessiter une \\u00e9valuation et un suivi m\\u00e9dical appropri\\u00e9s. Nos professionnels de la sant...\",\"inLanguage\":\"en-CA\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en\\\/#website\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en\\\/thrombocytopenie\\\/#breadcrumblist\"},\"datePublished\":\"2026-02-28T22:54:46-04:00\",\"dateModified\":\"2026-09-14T19:50:55-04:00\"},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en\\\/#website\",\"url\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en\\\/\",\"name\":\"Clinique Omicron\",\"description\":\"Clinique M\\u00e9dicale\",\"inLanguage\":\"en-CA\",\"publisher\":{\"@id\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en\\\/#organization\"}}]}\n\t\t<\/script>\n\t\t\r\n\t\t<title>Thrombocytop\u00e9nie | Clinique Omicron<\/title>\n\n","aioseo_head_json":{"title":"Thrombocytop\u00e9nie | Clinique Omicron","description":"Thrombocytopenia Thrombocytopenia is a medical condition that may require appropriate medical evaluation and monitoring. Our healthcare professionals...","canonical_url":"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/","robots":"max-snippet:-1, max-image-preview:large, max-video-preview:-1","keywords":"","webmasterTools":{"google-site-verification":"yYDMZv-nme7Cg-KrW5GmEWceBTrCDv8zhSkkXdJSnyM","msvalidate.01":"3225E6935FC4F40C7DDCE56C37141BA8","miscellaneous":""},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"BreadcrumbList","@id":"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/#breadcrumblist","itemListElement":[{"@type":"ListItem","@id":"https:\/\/cliniqueomicron.ca\/en#listItem","position":1,"name":"Accueil","item":"https:\/\/cliniqueomicron.ca\/en","nextItem":{"@type":"ListItem","@id":"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/#listItem","name":"Thrombocytop\u00e9nie : causes, diagnostic et traitement du d\u00e9ficit plaquettaire | Clinique Omicron"}},{"@type":"ListItem","@id":"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/#listItem","position":2,"name":"Thrombocytop\u00e9nie : causes, diagnostic et traitement du d\u00e9ficit plaquettaire | Clinique Omicron","previousItem":{"@type":"ListItem","@id":"https:\/\/cliniqueomicron.ca\/en#listItem","name":"Accueil"}}]},{"@type":"WebPage","@id":"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/#webpage","url":"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/","name":"Thrombocytop\u00e9nie | Clinique Omicron","description":"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...","inLanguage":"en-CA","isPartOf":{"@id":"https:\/\/cliniqueomicron.ca\/en\/#website"},"breadcrumb":{"@id":"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/#breadcrumblist"},"datePublished":"2026-02-28T22:54:46-04:00","dateModified":"2026-09-14T19:50:55-04:00"},{"@type":"WebSite","@id":"https:\/\/cliniqueomicron.ca\/en\/#website","url":"https:\/\/cliniqueomicron.ca\/en\/","name":"Clinique Omicron","description":"Clinique M\u00e9dicale","inLanguage":"en-CA","publisher":{"@id":"https:\/\/cliniqueomicron.ca\/en\/#organization"}}]},"og:locale":"en_US","og:site_name":"Clinique Omicron - Clinique M\u00e9dicale","og:type":"article","og:title":"Thrombocytopenie | Clinique Omicron Qu\u00e9bec","og:description":"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...","og:url":"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/","og:image":"https:\/\/cliniqueomicron.ca\/wp-content\/uploads\/2025\/12\/unnamed-1-e1765579964732.jpg","og:image:secure_url":"https:\/\/cliniqueomicron.ca\/wp-content\/uploads\/2025\/12\/unnamed-1-e1765579964732.jpg","article:published_time":"2026-03-01T02:54:46+00:00","article:modified_time":"2026-09-14T23:50:55+00:00","article:publisher":"https:\/\/www.facebook.com\/cliniqueomicron","twitter:card":"summary_large_image","twitter:site":"@CliniqueOmicron","twitter:title":"Thrombocytopenie | Clinique Omicron Qu\u00e9bec","twitter:description":"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...","twitter:creator":"@CliniqueOmicron","twitter:image":"https:\/\/cliniqueomicron.ca\/wp-content\/uploads\/2025\/12\/unnamed-1-e1765579964732.jpg"},"aioseo_meta_data":{"post_id":"25006","title":"Thrombocytop\u00e9nie | Clinique Omicron","description":"Thrombocytopenia Thrombocytopenia is a medical condition that may require appropriate medical evaluation and monitoring. Our healthcare professionals...","keywords":null,"keyphrases":{"focus":{"keyphrase":"thrombocytop\u00e9nie","score":75,"analysis":{"keyphraseInTitle":{"score":9,"maxScore":9,"error":0},"keyphraseInDescription":{"score":9,"maxScore":9,"error":0},"keyphraseLength":{"score":9,"maxScore":9,"error":0,"length":2},"keyphraseInURL":{"score":5,"maxScore":5,"error":0},"keyphraseInIntroduction":{"score":9,"maxScore":9,"error":0},"keyphraseInSubHeadings":{"score":3,"maxScore":9,"error":1},"keyphraseInImageAlt":[],"keywordDensity":{"type":"high","score":0,"maxScore":9,"error":1}}},"additional":[]},"primary_term":null,"canonical_url":null,"og_title":"Thrombocytopenie | Clinique Omicron Qu\u00e9bec","og_description":"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...","og_object_type":"default","og_image_type":"default","og_image_url":null,"og_image_width":null,"og_image_height":null,"og_image_custom_url":null,"og_image_custom_fields":null,"og_video":"","og_custom_url":null,"og_article_section":null,"og_article_tags":null,"twitter_use_og":true,"twitter_card":"summary_large_image","twitter_image_type":"default","twitter_image_url":null,"twitter_image_custom_url":null,"twitter_image_custom_fields":null,"twitter_title":"Thrombocytopenie | Clinique Omicron","twitter_description":"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...","schema":{"blockGraphs":[],"customGraphs":[],"default":{"data":{"Article":[],"Course":[],"Dataset":[],"FAQPage":[],"Movie":[],"Person":[],"Product":[],"ProductReview":[],"Car":[],"Recipe":[],"Service":[],"SoftwareApplication":[],"WebPage":[]},"graphName":"WebPage","isEnabled":true},"graphs":[]},"schema_type":"default","schema_type_options":null,"pillar_content":false,"robots_default":true,"robots_noindex":false,"robots_noarchive":false,"robots_nosnippet":false,"robots_nofollow":false,"robots_noimageindex":false,"robots_noodp":false,"robots_notranslate":false,"robots_max_snippet":"-1","robots_max_videopreview":"-1","robots_max_imagepreview":"large","priority":null,"frequency":"default","local_seo":null,"seo_analyzer_scan_date":"2026-09-15 00:15:11","breadcrumb_settings":null,"limit_modified_date":false,"reviewed_by":null,"open_ai":null,"ai":{"faqs":[],"keyPoints":[],"titles":[],"descriptions":[],"socialPosts":{"email":[],"linkedin":[],"twitter":[],"facebook":[],"instagram":[]}},"created":"2026-03-01 04:12:11","updated":"2026-09-15 00:24:33","focus_keyword":"thrombocytop\u00e9nie","additional_keywords":null,"truseo_locale":null},"aioseo_breadcrumb":"<div class=\"aioseo-breadcrumbs\"><span class=\"aioseo-breadcrumb\">\n\t<a href=\"https:\/\/cliniqueomicron.ca\/en\" title=\"Accueil\">Accueil<\/a>\n<\/span><span class=\"aioseo-breadcrumb-separator\">\u203a<\/span><span class=\"aioseo-breadcrumb\">\n\tThrombocytop\u00e9nie : causes, diagnostic et traitement du d\u00e9ficit plaquettaire | Clinique Omicron\n<\/span><\/div>","aioseo_breadcrumb_json":[{"label":"Accueil","link":"https:\/\/cliniqueomicron.ca\/en"},{"label":"Thrombocytop\u00e9nie : causes, diagnostic et traitement du d\u00e9ficit plaquettaire | Clinique Omicron","link":"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/"}],"_links":{"self":[{"href":"https:\/\/cliniqueomicron.ca\/en\/wp-json\/wp\/v2\/pages\/25006","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cliniqueomicron.ca\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/cliniqueomicron.ca\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/cliniqueomicron.ca\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cliniqueomicron.ca\/en\/wp-json\/wp\/v2\/comments?post=25006"}],"version-history":[{"count":4,"href":"https:\/\/cliniqueomicron.ca\/en\/wp-json\/wp\/v2\/pages\/25006\/revisions"}],"predecessor-version":[{"id":31871,"href":"https:\/\/cliniqueomicron.ca\/en\/wp-json\/wp\/v2\/pages\/25006\/revisions\/31871"}],"wp:attachment":[{"href":"https:\/\/cliniqueomicron.ca\/en\/wp-json\/wp\/v2\/media?parent=25006"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

\n\t\t\t\t

\n\t\t\t\t\t

\n\t\t\t\t

\n\t\t\t\t\t\n\n\n\n\nThrombocytopenia: Causes, Diagnosis, and Treatment of Platelet Deficiency | Clinique Omicron<\/title>\n<meta name=\"description\" content=\"La thrombocytop\u00e9nie est une r\u00e9duction des plaquettes sous 150 000\/\u00b5L causant un risque h\u00e9morragique. PTI, TIH, CIVD, m\u00e9dicaments, frottis plaquettes et prise en charge au Qu\u00e9bec.\">\n<meta name=\"keywords\" content=\"thrombocytop\u00e9nie, plaquettes basses, PTI purpura thrombop\u00e9nique idiopathique, TIH thrombocytop\u00e9nie h\u00e9parine, thrombocytop\u00e9nie m\u00e9dicamenteuse, CIVD thrombocytop\u00e9nie, thrombocytop\u00e9nie traitement, thrombocytop\u00e9nie causes, frottis plaquettes, thrombocytop\u00e9nie Qu\u00e9bec\">\n<link rel=\"preconnect\" href=\"https:\/\/fonts.googleapis.com\">\n<link href=\"https:\/\/fonts.googleapis.com\/css2?family=Cinzel:wght@600&family=Poppins:wght@400;500;600;700&display=swap\" rel=\"stylesheet\">\n<style>\n@import url('https:\/\/fonts.googleapis.com\/css2?family=Cinzel:wght@600&family=Poppins:wght@400;500;600;700&display=swap');\n\n.co-wrap * {\n font-family: 'Poppins', sans-serif;\n box-sizing: border-box;\n}\n.co-wrap {\n max-width: 1100px;\n margin: 0 auto;\n padding: 30px 0 60px;\n margin-top: 10px;\n}\n.co-label {\n font-family: 'Cinzel', serif;\n font-size: 14px;\n font-weight: bold;\n letter-spacing: 1px;\n text-transform: uppercase;\n color: #4D6577;\n margin-bottom: 14px;\n display: block;\n}\n.co-wrap h1 {\n font-size: 32px;\n font-weight: 500;\n color: #323C52;\n margin: 0 0 22px;\n line-height: 1.2;\n letter-spacing: 0.5px;\n}\n.co-intro {\n font-size: 16px;\n font-weight: 400;\n line-height: 1.75;\n color: #4D6577;\n margin-bottom: 36px;\n padding-bottom: 32px;\n border-bottom: 1px solid rgba(77,101,119,.2);\n}\n.co-wrap h2 {\n font-size: 20px;\n font-weight: 600;\n color: #323C52;\n margin: 32px 0 12px;\n letter-spacing: 0.3px;\n}\n.co-wrap p {\n font-size: 15px;\n font-weight: 400;\n color: #4D6577;\n line-height: 1.7;\n margin-bottom: 14px;\n}\n.co-list {\n list-style: none;\n padding: 0;\n margin: 12px 0 24px;\n}\n.co-list li {\n font-size: 15px;\n font-weight: 400;\n color: #4D6577;\n padding: 10px 14px 10px 38px;\n margin-bottom: 8px;\n border-radius: 6px;\n position: relative;\n background: rgba(77,101,119,.06);\n border-left: 3px solid #4D6577;\n}\n.co-list li::before {\n content: \"\u2713\";\n position: absolute;\n left: 12px;\n font-weight: 700;\n color: #4D6577;\n}\n.co-table {\n width: 100%;\n border-collapse: collapse;\n margin: 14px 0 22px;\n font-size: 14px;\n border-radius: 8px;\n overflow: hidden;\n}\n.co-table thead tr {\n background: #323C52;\n color: #fff;\n}\n.co-table thead th {\n padding: 11px 16px;\n text-align: left;\n font-weight: 600;\n font-size: 13px;\n}\n.co-table tbody tr:nth-child(even) {\n background: rgba(77,101,119,.06);\n}\n.co-table tbody tr:nth-child(odd) {\n background: #fff;\n}\n.co-table td {\n padding: 10px 16px;\n color: #4D6577;\n border-bottom: 1px solid rgba(77,101,119,.12);\n font-size: 14px;\n vertical-align: top;\n}\n.co-table td:first-child {\n font-weight: 600;\n color: #323C52;\n}\n.co-infobox {\n display: flex;\n gap: 12px;\n background: rgba(77,101,119,.06);\n border-radius: 8px;\n border-left: 4px solid #4D6577;\n padding: 14px 18px;\n margin: 18px 0 28px;\n font-size: 14px;\n font-weight: 400;\n color: #4D6577;\n line-height: 1.65;\n}\n.co-infobox .ico {\n font-size: 18px;\n flex-shrink: 0;\n}\n.co-urgence {\n background: #fff8f8;\n border-left: 5px solid #c0392b;\n border-radius: 6px;\n padding: 20px 26px;\n margin: 24px 0 32px;\n}\n.co-urgence .co-urgence-titre {\n font-size: 13px;\n font-weight: 700;\n color: #c0392b;\n letter-spacing: 1.5px;\n text-transform: uppercase;\n margin-bottom: 10px;\n}\n.co-urgence p {\n color: #5a2020;\n font-size: 14px;\n margin: 0 0 10px;\n line-height: 1.7;\n}\n.co-urgence p:last-child {\n margin-bottom: 0;\n}\n.co-disclaimer {\n font-size: 13px;\n color: #8a9aaa;\n font-style: italic;\n border-top: 1px solid rgba(77,101,119,.15);\n padding-top: 24px;\n margin-top: 40px;\n line-height: 1.6;\n}\n<\/style>\n<\/head>\n<body>\n<div class=\"co-wrap\">\n\n <span class=\"co-label\">Hematology & Internal Medicine & Family Medicine<\/span>\n <h1>Thrombocytop\u00e9nie<\/h1>\n<style>.oc-fiche-cta{margin:8px 0 34px;padding:22px 24px;border:1.5px solid rgba(50,60,82,.15);border-left:4px solid #FF611C;border-radius:12px;background:#F4F6F8;font-family:Poppins,sans-serif}.oc-fiche-cta-t{font-size:18px;font-weight:600;color:#323C52;margin:0 0 4px;line-height:1.35}.oc-fiche-cta-x{font-size:15px;color:#4D6577;margin:0 0 14px;line-height:1.55}.oc-fiche-cta-b{display:flex;flex-wrap:wrap;gap:10px}.oc-fiche-cta-b a{display:inline-flex;align-items:center;justify-content:center;min-height:44px;padding:10px 18px;border-radius:8px;font-size:14px;font-weight:600;text-decoration:none;box-sizing:border-box}.oc-fiche-cta-b .oc-p{background:#FF611C;color:#fff}.oc-fiche-cta-b .oc-p:hover{background:#E04E0C}.oc-fiche-cta-b .oc-s{background:#fff;color:#323C52;border:1.5px solid rgba(50,60,82,.25)}@media (max-width:600px){.co-wrap h1{font-size:24px;line-height:1.25;text-transform:none}.oc-fiche-cta{padding:18px 16px}.oc-fiche-cta-b a{flex:1 1 100%}body .co-wrap > .co-table,body .co-wrap > .co-table tbody,body .co-wrap > .co-table tr,body .co-wrap > .co-table td{display:block;width:100%;box-sizing:border-box}body .co-wrap > .co-table{min-width:0;table-layout:auto}body .co-wrap > .co-table thead{display:none}body .co-wrap > .co-table tr{margin:0 0 10px;border:1px solid rgba(77,101,119,.18);border-radius:8px;overflow:hidden}body .co-wrap > .co-table td{padding:9px 12px;border:0}body .co-wrap > .co-table td:first-child{font-weight:600;color:#323C52;background:rgba(77,101,119,.07)}#ocw{transform:scale(.8);transform-origin:bottom right}}<\/style><div class=\"oc-fiche-cta\" data-oc-cta=\"fiche-haut-consult\"><p class=\"oc-fiche-cta-t\">Obtenir un avis adapt\u00e9 \u00e0 votre situation<\/p><p class=\"oc-fiche-cta-x\">Consultation en clinique ou en t\u00e9l\u00e9consultation, partout au Qu\u00e9bec.<\/p><div class=\"oc-fiche-cta-b\"><a class=\"oc-p\" href=\"https:\/\/cliniqueomicron.ca\/rendez-vous\/\">Make an appointment<\/a><a class=\"oc-s\" href=\"https:\/\/cliniqueomicron.ca\/consultation-en-ligne\/\">Consult online<\/a><a class=\"oc-s\" href=\"tel:+15146063350\">514 606-3350<\/a><\/div><\/div>\n\n\n <div class=\"co-intro\">\n La thrombocytop\u00e9nie (ou thrombop\u00e9nie) est d\u00e9finie par une num\u00e9ration plaquettaire inf\u00e9rieure \u00e0 150 000 plaquettes par microlitre (\u00b5L) de sang \u2014 la valeur normale \u00e9tant de 150 000\u2013400 000\/\u00b5L \u2014 r\u00e9sultant soit d'une production insuffisante de plaquettes dans la moelle osseuse + soit d'une destruction acc\u00e9l\u00e9r\u00e9e des plaquettes en p\u00e9riph\u00e9rie (immunologique + m\u00e9canique + consommation) + soit d'une s\u00e9questration excessive dans la rate (hyperspl\u00e9nisme) + soit d'une dilution dans un contexte de transfusions massives. La gravit\u00e9 clinique de la thrombocytop\u00e9nie est directement corr\u00e9l\u00e9e au chiffre de plaquettes : thrombocytop\u00e9nie l\u00e9g\u00e8re (100 000\u2013150 000\/\u00b5L) \u2192 risque h\u00e9morragique minimal + g\u00e9n\u00e9ralement asymptomatique + thrombocytop\u00e9nie mod\u00e9r\u00e9e (50 000\u2013100 000\/\u00b5L) \u2192 saignements possibles lors de traumatismes ou de chirurgies + thrombocytop\u00e9nie s\u00e9v\u00e8re (20 000\u201350 000\/\u00b5L) \u2192 risque h\u00e9morragique spontan\u00e9 + purpura + \u00e9pistaxis + m\u00e9norragies + thrombocytop\u00e9nie tr\u00e8s s\u00e9v\u00e8re (<20 000\/\u00b5L) \u2192 risque d'h\u00e9morragie c\u00e9r\u00e9brale spontan\u00e9e + h\u00e9morragie visc\u00e9rale + urgence m\u00e9dicale. Le frottis sanguin est l'examen fondamental initial : il permet de confirmer la thrombocytop\u00e9nie (exclure la pseudothrombocytop\u00e9nie sur EDTA) + d'\u00e9valuer la morphologie des plaquettes (macroplaquettes = production acc\u00e9l\u00e9r\u00e9e + microplaquettes = syndrome de Wiskott-Aldrich) + et de rechercher des anomalies associ\u00e9es des autres lign\u00e9es (schizocytes \u2192 MAT + blastes \u2192 leuc\u00e9mie + corps de D\u00f6hle + granulations toxiques \u2192 sepsis) qui orientent le diagnostic \u00e9tiologique.\n <\/div>\n\n <h2>D\u00e9marche diagnostique initiale<\/h2>\n <ul class=\"co-list\">\n <li><strong>Confirmer la thrombocytop\u00e9nie \u2014 exclure la pseudothrombocytop\u00e9nie :<\/strong> Repeat NFS on citrate (blue) tube or on heparin tube \u2192 if platelets normal = pseudothrombocytopenia on EDTA (artefactual platelet agglutination in the presence of EDTA by EDTA-dependent anti-platelet antibodies \u2192 falsely low on the analyzer) \u2192 frequent (0.1\u20130.3 % of the population) + benign + without clinical significance<\/li>\n <li><strong>Manual blood smear:<\/strong> confirm thrombocytopenia + evaluate platelet size + look for aggregates (clumping) + schistocytes (MAT) + blasts (acute leukemia) + atypical lymphocytes (EBV) + D\u00f6hle bodies (infection)<\/li>\n <li><strong>Anamn\u00e8se cibl\u00e9e :<\/strong> Medications (ALL medications + including over-the-counter medications + supplements + and recently discontinued medications) + alcohol + recent infections + history of bleeding + family history + pregnancy + recent transfusions + HIV + Hepatitis C + Lupus + recent surgery + hemodialysis<\/li>\n <li><strong>Physical examination :<\/strong> purpura (petechiae + ecchymoses) + splenomegaly (hypersplenism + portal hypertension + lymphoma) + lymphadenopathy (lymphoma) + signs of chronic liver disease + signs of SLE (malar rash) + signs of sepsis<\/li>\n <\/ul>\n\n <h2>Causes de thrombocytop\u00e9nie par m\u00e9canisme<\/h2>\n\n <table class=\"co-table\">\n <thead>\n <tr>\n <th>Mechanism<\/th>\n <th>Main causes<\/th>\n <th>\u00c9l\u00e9ments orientants<\/th>\n <\/tr>\n <\/thead>\n <tbody>\n <tr>\n <td>Destruction immune (anti-platelet antibodies)<\/td>\n <td>PTI (purpura thrombop\u00e9nique immunologique) + TIH (thrombocytop\u00e9nie induite par l'h\u00e9parine) + thrombocytop\u00e9nie m\u00e9dicamenteuse (quinine + vancomycine + lin\u00e9zolide + c\u00e9phalosporines + etc.) + lupus + VIH + VHC + grossesse (HELLP + thrombocytop\u00e9nie gestationnelle)<\/td>\n <td>Moelle osseuse riche en m\u00e9gacaryocytes (production compensatrice acc\u00e9l\u00e9r\u00e9e) + macroplaquettes au frottis + Coombs pour anti-plaquettes (test de Dixon) + anticorps anti-plaquettes + bilan auto-immun<\/td>\n <\/tr>\n <tr>\n <td>Thrombotic Microangiopathy (TMA)<\/td>\n <td>PTT (purpura thrombotique thrombocytop\u00e9nique) + SHU + HELLP + CIVD + HTA maligne + MAT m\u00e9dicamenteuse<\/td>\n <td>Schizocytes +++ au frottis + Coombs n\u00e9gatif + LDH \u00e9lev\u00e9e + haptoglobine effondr\u00e9e + cr\u00e9atinine \u00e9lev\u00e9e + ADAMTS13 < 10 % si PTT \u2192 traitement par \u00e9changes plasmatiques en urgence<\/td>\n <\/tr>\n <tr>\n <td>Consumption (CIVD)<\/td>\n <td>Sepsis + trauma s\u00e9v\u00e8re + cancer + br\u00fblures + embolie amniotique + HELLP<\/td>\n <td>TP allong\u00e9 + APTT allong\u00e9 + fibrinog\u00e8ne bas + D-dim\u00e8res tr\u00e8s \u00e9lev\u00e9s + schizocytes possibles + contexte de choc ou infection s\u00e9v\u00e8re<\/td>\n <\/tr>\n <tr>\n <td>Insufficient production (power plants)<\/td>\n <td>Aplasie m\u00e9dullaire + leuc\u00e9mie aigu\u00eb + SMD (syndrome my\u00e9lodysplasique) + chimioth\u00e9rapie + radioth\u00e9rapie + envahissement m\u00e9dullaire (m\u00e9tastases + lymphome) + carence B12\/folates + alcoolisme (toxicit\u00e9 directe sur la moelle) + infection virale (VIH + EBV + CMV + parvovirus B19)<\/td>\n <td>Bi- ou pancytop\u00e9nie + microplaquettes ou plaquettes normales (pas de macroplaquettes) + my\u00e9logramme\/biopsie ost\u00e9om\u00e9dullaire + LDH \u00e9lev\u00e9e si h\u00e9mopathie maligne<\/td>\n <\/tr>\n <tr>\n <td>S\u00e9questration spl\u00e9nique<\/td>\n <td>Hypertension portale (cirrhose) + spl\u00e9nom\u00e9galie congestive + lymphome + sarco\u00efdose + leishmaniose<\/td>\n <td>Spl\u00e9nom\u00e9galie \u00e0 l'\u00e9chographie + thrombocytop\u00e9nie mod\u00e9r\u00e9e (40 000\u2013100 000\/\u00b5L) + souvent pancytop\u00e9nie + signes de cirrhose ou de maladie de base<\/td>\n <\/tr>\n <\/tbody>\n <\/table>\n\n <h2>PTI (Purpura Thrombop\u00e9nique Immunologique) \u2014 d\u00e9tails<\/h2>\n <ul class=\"co-list\">\n <li><strong>Definition:<\/strong> Immune thrombocytopenia + anti-platelet autoantibodies (anti-GPIIb-IIIa + anti-GPIb) + in the absence of other identifiable causes + diagnosis of exclusion<\/li>\n <li><strong>Shapes<\/strong> PTI aigu (enfant + souvent post-viral + gu\u00e9rison spontan\u00e9e dans 80\u201390 % en 6 mois) + PTI chronique (adulte + femme jeune ++ + persiste > 12 mois) + PTI secondaire (lupus + VIH + VHC + m\u00e9dicaments)<\/li>\n <li><strong>Balance<\/strong> NFS + Pap smear + group + RAI + HIV serology + HCV + autoimmune workup (ANA) + H. pylori (to be treated if positive \u2192 possible resolution of ITP) + in children: no bone marrow aspiration if typical presentation<\/li>\n <li><strong>Treatment (adult):<\/strong> plaquettes > 30 000 sans saignement \u2192 surveillance + plaquettes < 30 000 + ou saignements : cortico\u00efdes (prednisone 1 mg\/kg\/j \u00d7 4 semaines) + ou dexam\u00e9thasone 40 mg\/j \u00d7 4 jours (r\u00e9ponse plus rapide) + IgIV 1 g\/kg\/j \u00d7 1\u20132 jours (urgence + pr\u00e9-op\u00e9ratoire) + si r\u00e9fractaire : rituximab (375 mg\/m\u00b2 \u00d7 4 semaines) + eltrombopag + avatrombopag + romiplostim (agonistes du r\u00e9cepteur de la thrombopo\u00ef\u00e9tine) + spl\u00e9nectomie (r\u00e9mission 60\u201370 % \u00e0 long terme)<\/li>\n <\/ul>\n\n <h2>TIH (Thrombocytop\u00e9nie Induite par l'H\u00e9parine) \u2014 urgence m\u00e9dicale<\/h2>\n <ul class=\"co-list\">\n <li><strong>M\u00e9canisme :<\/strong> IgG antibodies anti-heparin-PF4 (platelet factor 4) complex \u2192 platelet activation \u2192 thrombocytopenia + paradoxical thromboses (venous + arterial) \u2192 HIT = PROthrombotic thrombocytopenia (the risk is not bleeding but thrombosis)<\/li>\n <li><strong>Crit\u00e8res cliniques \u2014 score 4T :<\/strong> Thrombocytop\u00e9nie (chute > 50 % ou nadir 20 000\u2013100 000) + Timing (chute J5\u2013J10 sous h\u00e9parine + ou < J1 si exposition r\u00e9cente) + Thrombose (nouvelle thrombose + ou n\u00e9crose cutan\u00e9e au site d'injection) + autres causes de Thrombocytop\u00e9nie absentes \u2192 score 0\u20138 : 0\u20133 = probabilit\u00e9 faible + 4\u20135 = interm\u00e9diaire + 6\u20138 = \u00e9lev\u00e9e<\/li>\n <li><strong>Conduite \u00e0 tenir si TIH suspect\u00e9e :<\/strong> IMMEDIATELY STOP all heparin (UFH + LMWH + heparinized catheter) + DO NOT transfuse platelets (worsens thrombosis) + SUBSTITUTE with non-heparin anticoagulant \u2192 argatroban (IV) + fondaparinux (SC) + bivalirudin + danaparoid + anti-PF4\/heparin serology (ELISA) + platelet activation test (HIPA)<\/li>\n <li><strong>Warfarin in the treatment of VTE:<\/strong> DO NOT initiate warfarin during the acute phase (risk of skin necrosis + limb gangrene due to protein C drop before sufficient anticoagulation).<\/li>\n <\/ul>\n\n <div class=\"co-infobox\">\n <span class=\"ico\">\u2119\ufe0f<\/span>\n <span>La thrombocytop\u00e9nie induite par l'h\u00e9parine (TIH) est un paradoxe clinique essentiel : c'est une thrombocytop\u00e9nie PROTHROMBOTIQUE et non h\u00e9morragique. Arr\u00eater l'h\u00e9parine imm\u00e9diatement d\u00e8s la suspicion + NE JAMAIS transfuser des plaquettes (risque d'aggraver les thromboses \u2014 les plaquettes sont du carburant pour les thrombi dans la TIH) + substituer imm\u00e9diatement par un anticoagulant non h\u00e9parinique. Une thrombose (TVP + EP + art\u00e9rielle + CIVD) dans les 5 \u00e0 10 jours suivant le d\u00e9but d'une h\u00e9parine doit faire syst\u00e9matiquement \u00e9voquer une TIH.<\/span>\n <\/div>\n\n <h2>Platelet transfusion thresholds<\/h2>\n <ul class=\"co-list\">\n <li><strong>Plaquettes < 10 000\/\u00b5L :<\/strong> prophylactic transfusion in the absence of bleeding (prevention of spontaneous intracranial hemorrhage)<\/li>\n <li><strong>Plaquettes < 20 000\/\u00b5L + fi\u00e8vre + coagulopathie :<\/strong> prophylactic transfusion<\/li>\n <li><strong>Plaquettes < 50 000\/\u00b5L + geste invasif pr\u00e9vu (ponction lombaire + endoscopie avec biopsie + chirurgie mineure) :<\/strong> Pre-procedure transfusion<\/li>\n <li><strong>Plaquettes < 100 000\/\u00b5L + neurochirurgie + chirurgie ophtalmique :<\/strong> Preoperative transfusion<\/li>\n <li><strong>Contre-indications absolues \u00e0 la transfusion de plaquettes :<\/strong> PTT + TIH + SHU \u2192 worsening of microvascular thrombosis<\/li>\n <\/ul>\n\n <div class=\"co-urgence\">\n <div class=\"co-urgence-titre\">Medical emergencies<\/div>\n <p>Se rendre imm\u00e9diatement aux urgences si une thrombocytop\u00e9nie s\u00e9v\u00e8re (< 20 000\/\u00b5L) est d\u00e9couverte + ou si des saignements spontan\u00e9s (p\u00e9t\u00e9chies diffuses + h\u00e9morragie nasale ou buccale incoercible + sang dans les urines ou les selles) apparaissent + ou si une chute brutale des plaquettes survient chez un patient sous h\u00e9parine (\u00e9voquer une TIH \u2014 arr\u00eater imm\u00e9diatement l'h\u00e9parine). Pour le bilan initial d'une thrombocytop\u00e9nie l\u00e9g\u00e8re \u00e0 mod\u00e9r\u00e9e d\u00e9couverte fortuitement et l'orientation vers l'h\u00e9matologie, Clinique Omicron offre des consultations m\u00e9dicales dans ses points de service au Qu\u00e9bec et en t\u00e9l\u00e9m\u00e9decine. Pour prendre rendez-vous, visitez <a href=\"https:\/\/cliniqueomicron.ca\" style=\"color:#c0392b;font-weight:600;text-decoration:none;\">cliniqueomicron.ca<\/a>.<\/p>\n <\/div>\n\n <h2>Consult at Clinique Omicron<\/h2>\n <p>Les m\u00e9decins et infirmiers praticiens sp\u00e9cialis\u00e9s (IPS) de Clinique Omicron confirment la thrombocytop\u00e9nie par le frottis sanguin (exclure la pseudothrombocytop\u00e9nie sur EDTA), prescrivent le bilan \u00e9tiologique orient\u00e9 (s\u00e9rologie VIH + VHC + bilan auto-immun + bilan de MAT si schizocytes), identifient les m\u00e9dicaments causaux (TIH + thrombocytop\u00e9nie m\u00e9dicamenteuse), initient la prednisone pour le PTI, orientent en urgence vers l'h\u00e9matologie pour les thrombocytop\u00e9nies s\u00e9v\u00e8res ou les MAT (PTT \u2192 \u00e9changes plasmatiques en urgence), et assurent le suivi des PTI chroniques. Des consultations sont disponibles dans plusieurs points de service au Qu\u00e9bec et en t\u00e9l\u00e9m\u00e9decine. Pour prendre rendez-vous, visitez <a href=\"https:\/\/cliniqueomicron.ca\" style=\"color:#4D6577;font-weight:600;text-decoration:none;\">cliniqueomicron.ca<\/a>.<\/p>\n\n <p class=\"co-disclaimer\">Le contenu de cette page est fourni \u00e0 titre informatif uniquement et ne remplace pas l'avis d'un m\u00e9decin ou d'un h\u00e9matologue. La thrombocytop\u00e9nie induite par l'h\u00e9parine (TIH) est une urgence m\u00e9dicale \u2014 arr\u00eater l'h\u00e9parine imm\u00e9diatement et NE PAS transfuser des plaquettes. Un PTT (purpura thrombotique thrombocytop\u00e9nique) avec ADAMTS13 < 10 % n\u00e9cessite des \u00e9changes plasmatiques en urgence absolue.<\/p>\n\n<\/div>\n<\/body>\n<\/html>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Thrombocytop\u00e9nie : causes, diagnostic et traitement du d\u00e9ficit plaquettaire | Clinique Omicron H\u00e9matologie & M\u00e9decine interne & M\u00e9decine de famille Thrombocytop\u00e9nie La thrombocytop\u00e9nie (ou thrombop\u00e9nie) est d\u00e9finie par une num\u00e9ration plaquettaire inf\u00e9rieure \u00e0 150 000 plaquettes par microlitre (\u00b5L) de sang \u2014 la valeur normale \u00e9tant de 150 000\u2013400 000\/\u00b5L \u2014 r\u00e9sultant soit d’une production… <a href=\"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/\" rel=\"bookmark\">Read More \"<span class=\"screen-reader-text\">Thrombocytopenia: Causes, Diagnosis, and Treatment of Platelet Deficiency | Clinique Omicron<\/span><\/a><\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"off","neve_meta_content_width":100,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"","_themeisle_gutenberg_block_has_review":false,"_metasync_otto_title":"Thrombocytop\u00e9nie | Brossard | Clinique Omicron","_metasync_otto_description":"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...","_metasync_otto_keywords":"","_metasync_otto_og_title":"Thrombocytopenie | Clinique Omicron Qu\u00e9bec","_metasync_otto_og_description":"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...","_metasync_otto_twitter_title":"Thrombocytopenie | Clinique Omicron","_metasync_otto_twitter_description":"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...","rank_math_title":"","rank_math_description":"","_yoast_wpseo_title":"","_yoast_wpseo_metadesc":"","_aioseo_title":"Thrombocytop\u00e9nie : causes, diagnostic et traitement du d\u00e9ficit plaquettaire | Clinique Omicron","_aioseo_description":"La thrombocytop\u00e9nie est une r\u00e9duction des plaquettes <150 000\/\u00b5L. PTI prednisone rituximab eltrombopag, TIH arr\u00eater h\u00e9parine NE PAS transfuser anti-FP4, schizocytes PTT \u00e9changes plasmatiques urgence, frottis EDTA au Qu\u00e9bec.","_metasync_seo_title":"Thrombocytop\u00e9nie | Clinique Omicron","_metasync_seo_desc":"","_metasync_breadcrumb_title":"","_metasync_primary_category":0,"_metasync_primary_product_cat":0,"_metasync_imported_seo_title":"","_metasync_imported_seo_desc":"","_metasync_otto_disabled":"","_metasync_hreflang":"","_metasync_plugin_sync_ts":"{\"aioseo\":\"2026-09-03T07:53:13+00:00\"}","_metasync_robots_advanced":"","_metasync_og_title":"Thrombocytopenie | Clinique Omicron Qu\u00e9bec","_metasync_og_description":"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...","_metasync_twitter_title":"Thrombocytopenie | Clinique Omicron","_metasync_twitter_description":"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...","footnotes":""},"class_list":["post-25006","page","type-page","status-publish","hentry"],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t<meta name=\"description\" content=\"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...\" \/>\n\t<meta name=\"robots\" content=\"max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n\t<meta name=\"google-site-verification\" content=\"yYDMZv-nme7Cg-KrW5GmEWceBTrCDv8zhSkkXdJSnyM\" \/>\n\t<meta name=\"msvalidate.01\" content=\"3225E6935FC4F40C7DDCE56C37141BA8\" \/>\n\t<link rel=\"canonical\" href=\"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO Pro (AIOSEO) 5.0.1.1\" \/>\n\t\t<meta property=\"og:locale\" content=\"en_US\" \/>\n\t\t<meta property=\"og:site_name\" content=\"Clinique Omicron - Clinique M\u00e9dicale\" \/>\n\t\t<meta property=\"og:type\" content=\"article\" \/>\n\t\t<meta property=\"og:title\" content=\"Thrombocytopenie | Clinique Omicron Qu\u00e9bec\" \/>\n\t\t<meta property=\"og:description\" content=\"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...\" \/>\n\t\t<meta property=\"og:url\" content=\"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/\" \/>\n\t\t<meta property=\"og:image\" content=\"https:\/\/cliniqueomicron.ca\/wp-content\/uploads\/2025\/12\/unnamed-1-e1765579964732.jpg\" \/>\n\t\t<meta property=\"og:image:secure_url\" content=\"https:\/\/cliniqueomicron.ca\/wp-content\/uploads\/2025\/12\/unnamed-1-e1765579964732.jpg\" \/>\n\t\t<meta property=\"article:published_time\" content=\"2026-03-01T02:54:46+00:00\" \/>\n\t\t<meta property=\"article:modified_time\" content=\"2026-09-14T23:50:55+00:00\" \/>\n\t\t<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/cliniqueomicron\" \/>\n\t\t<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n\t\t<meta name=\"twitter:site\" content=\"@CliniqueOmicron\" \/>\n\t\t<meta name=\"twitter:title\" content=\"Thrombocytopenie | Clinique Omicron Qu\u00e9bec\" \/>\n\t\t<meta name=\"twitter:description\" content=\"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...\" \/>\n\t\t<meta name=\"twitter:creator\" content=\"@CliniqueOmicron\" \/>\n\t\t<meta name=\"twitter:image\" content=\"https:\/\/cliniqueomicron.ca\/wp-content\/uploads\/2025\/12\/unnamed-1-e1765579964732.jpg\" \/>\n\t\t<script type=\"application\/ld+json\" class=\"aioseo-schema\">\n\t\t\t{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en\\\/thrombocytopenie\\\/#breadcrumblist\",\"itemListElement\":[{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en#listItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en\",\"nextItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en\\\/thrombocytopenie\\\/#listItem\",\"name\":\"Thrombocytop\\u00e9nie : causes, diagnostic et traitement du d\\u00e9ficit plaquettaire | Clinique Omicron\"}},{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en\\\/thrombocytopenie\\\/#listItem\",\"position\":2,\"name\":\"Thrombocytop\\u00e9nie : causes, diagnostic et traitement du d\\u00e9ficit plaquettaire | Clinique Omicron\",\"previousItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en#listItem\",\"name\":\"Accueil\"}}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en\\\/thrombocytopenie\\\/#webpage\",\"url\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en\\\/thrombocytopenie\\\/\",\"name\":\"Thrombocytop\\u00e9nie | Clinique Omicron\",\"description\":\"Thrombocytop\\u00e9nie Thrombocytop\\u00e9nie est une condition m\\u00e9dicale qui peut n\\u00e9cessiter une \\u00e9valuation et un suivi m\\u00e9dical appropri\\u00e9s. Nos professionnels de la sant...\",\"inLanguage\":\"en-CA\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en\\\/#website\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en\\\/thrombocytopenie\\\/#breadcrumblist\"},\"datePublished\":\"2026-02-28T22:54:46-04:00\",\"dateModified\":\"2026-09-14T19:50:55-04:00\"},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en\\\/#website\",\"url\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en\\\/\",\"name\":\"Clinique Omicron\",\"description\":\"Clinique M\\u00e9dicale\",\"inLanguage\":\"en-CA\",\"publisher\":{\"@id\":\"https:\\\/\\\/cliniqueomicron.ca\\\/en\\\/#organization\"}}]}\n\t\t<\/script>\n\t\t\r\n\t\t<title>Thrombocytop\u00e9nie | Clinique Omicron<\/title>\n\n","aioseo_head_json":{"title":"Thrombocytop\u00e9nie | Clinique Omicron","description":"Thrombocytopenia Thrombocytopenia is a medical condition that may require appropriate medical evaluation and monitoring. Our healthcare professionals...","canonical_url":"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/","robots":"max-snippet:-1, max-image-preview:large, max-video-preview:-1","keywords":"","webmasterTools":{"google-site-verification":"yYDMZv-nme7Cg-KrW5GmEWceBTrCDv8zhSkkXdJSnyM","msvalidate.01":"3225E6935FC4F40C7DDCE56C37141BA8","miscellaneous":""},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"BreadcrumbList","@id":"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/#breadcrumblist","itemListElement":[{"@type":"ListItem","@id":"https:\/\/cliniqueomicron.ca\/en#listItem","position":1,"name":"Accueil","item":"https:\/\/cliniqueomicron.ca\/en","nextItem":{"@type":"ListItem","@id":"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/#listItem","name":"Thrombocytop\u00e9nie : causes, diagnostic et traitement du d\u00e9ficit plaquettaire | Clinique Omicron"}},{"@type":"ListItem","@id":"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/#listItem","position":2,"name":"Thrombocytop\u00e9nie : causes, diagnostic et traitement du d\u00e9ficit plaquettaire | Clinique Omicron","previousItem":{"@type":"ListItem","@id":"https:\/\/cliniqueomicron.ca\/en#listItem","name":"Accueil"}}]},{"@type":"WebPage","@id":"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/#webpage","url":"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/","name":"Thrombocytop\u00e9nie | Clinique Omicron","description":"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...","inLanguage":"en-CA","isPartOf":{"@id":"https:\/\/cliniqueomicron.ca\/en\/#website"},"breadcrumb":{"@id":"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/#breadcrumblist"},"datePublished":"2026-02-28T22:54:46-04:00","dateModified":"2026-09-14T19:50:55-04:00"},{"@type":"WebSite","@id":"https:\/\/cliniqueomicron.ca\/en\/#website","url":"https:\/\/cliniqueomicron.ca\/en\/","name":"Clinique Omicron","description":"Clinique M\u00e9dicale","inLanguage":"en-CA","publisher":{"@id":"https:\/\/cliniqueomicron.ca\/en\/#organization"}}]},"og:locale":"en_US","og:site_name":"Clinique Omicron - Clinique M\u00e9dicale","og:type":"article","og:title":"Thrombocytopenie | Clinique Omicron Qu\u00e9bec","og:description":"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...","og:url":"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/","og:image":"https:\/\/cliniqueomicron.ca\/wp-content\/uploads\/2025\/12\/unnamed-1-e1765579964732.jpg","og:image:secure_url":"https:\/\/cliniqueomicron.ca\/wp-content\/uploads\/2025\/12\/unnamed-1-e1765579964732.jpg","article:published_time":"2026-03-01T02:54:46+00:00","article:modified_time":"2026-09-14T23:50:55+00:00","article:publisher":"https:\/\/www.facebook.com\/cliniqueomicron","twitter:card":"summary_large_image","twitter:site":"@CliniqueOmicron","twitter:title":"Thrombocytopenie | Clinique Omicron Qu\u00e9bec","twitter:description":"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...","twitter:creator":"@CliniqueOmicron","twitter:image":"https:\/\/cliniqueomicron.ca\/wp-content\/uploads\/2025\/12\/unnamed-1-e1765579964732.jpg"},"aioseo_meta_data":{"post_id":"25006","title":"Thrombocytop\u00e9nie | Clinique Omicron","description":"Thrombocytopenia Thrombocytopenia is a medical condition that may require appropriate medical evaluation and monitoring. Our healthcare professionals...","keywords":null,"keyphrases":{"focus":{"keyphrase":"thrombocytop\u00e9nie","score":75,"analysis":{"keyphraseInTitle":{"score":9,"maxScore":9,"error":0},"keyphraseInDescription":{"score":9,"maxScore":9,"error":0},"keyphraseLength":{"score":9,"maxScore":9,"error":0,"length":2},"keyphraseInURL":{"score":5,"maxScore":5,"error":0},"keyphraseInIntroduction":{"score":9,"maxScore":9,"error":0},"keyphraseInSubHeadings":{"score":3,"maxScore":9,"error":1},"keyphraseInImageAlt":[],"keywordDensity":{"type":"high","score":0,"maxScore":9,"error":1}}},"additional":[]},"primary_term":null,"canonical_url":null,"og_title":"Thrombocytopenie | Clinique Omicron Qu\u00e9bec","og_description":"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...","og_object_type":"default","og_image_type":"default","og_image_url":null,"og_image_width":null,"og_image_height":null,"og_image_custom_url":null,"og_image_custom_fields":null,"og_video":"","og_custom_url":null,"og_article_section":null,"og_article_tags":null,"twitter_use_og":true,"twitter_card":"summary_large_image","twitter_image_type":"default","twitter_image_url":null,"twitter_image_custom_url":null,"twitter_image_custom_fields":null,"twitter_title":"Thrombocytopenie | Clinique Omicron","twitter_description":"Thrombocytop\u00e9nie Thrombocytop\u00e9nie est une condition m\u00e9dicale qui peut n\u00e9cessiter une \u00e9valuation et un suivi m\u00e9dical appropri\u00e9s. Nos professionnels de la sant...","schema":{"blockGraphs":[],"customGraphs":[],"default":{"data":{"Article":[],"Course":[],"Dataset":[],"FAQPage":[],"Movie":[],"Person":[],"Product":[],"ProductReview":[],"Car":[],"Recipe":[],"Service":[],"SoftwareApplication":[],"WebPage":[]},"graphName":"WebPage","isEnabled":true},"graphs":[]},"schema_type":"default","schema_type_options":null,"pillar_content":false,"robots_default":true,"robots_noindex":false,"robots_noarchive":false,"robots_nosnippet":false,"robots_nofollow":false,"robots_noimageindex":false,"robots_noodp":false,"robots_notranslate":false,"robots_max_snippet":"-1","robots_max_videopreview":"-1","robots_max_imagepreview":"large","priority":null,"frequency":"default","local_seo":null,"seo_analyzer_scan_date":"2026-09-15 00:15:11","breadcrumb_settings":null,"limit_modified_date":false,"reviewed_by":null,"open_ai":null,"ai":{"faqs":[],"keyPoints":[],"titles":[],"descriptions":[],"socialPosts":{"email":[],"linkedin":[],"twitter":[],"facebook":[],"instagram":[]}},"created":"2026-03-01 04:12:11","updated":"2026-09-15 00:24:33","focus_keyword":"thrombocytop\u00e9nie","additional_keywords":null,"truseo_locale":null},"aioseo_breadcrumb":"<div class=\"aioseo-breadcrumbs\"><span class=\"aioseo-breadcrumb\">\n\t<a href=\"https:\/\/cliniqueomicron.ca\/en\" title=\"Accueil\">Accueil<\/a>\n<\/span><span class=\"aioseo-breadcrumb-separator\">\u203a<\/span><span class=\"aioseo-breadcrumb\">\n\tThrombocytop\u00e9nie : causes, diagnostic et traitement du d\u00e9ficit plaquettaire | Clinique Omicron\n<\/span><\/div>","aioseo_breadcrumb_json":[{"label":"Accueil","link":"https:\/\/cliniqueomicron.ca\/en"},{"label":"Thrombocytop\u00e9nie : causes, diagnostic et traitement du d\u00e9ficit plaquettaire | Clinique Omicron","link":"https:\/\/cliniqueomicron.ca\/en\/thrombocytopenie\/"}],"_links":{"self":[{"href":"https:\/\/cliniqueomicron.ca\/en\/wp-json\/wp\/v2\/pages\/25006","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cliniqueomicron.ca\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/cliniqueomicron.ca\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/cliniqueomicron.ca\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cliniqueomicron.ca\/en\/wp-json\/wp\/v2\/comments?post=25006"}],"version-history":[{"count":4,"href":"https:\/\/cliniqueomicron.ca\/en\/wp-json\/wp\/v2\/pages\/25006\/revisions"}],"predecessor-version":[{"id":31871,"href":"https:\/\/cliniqueomicron.ca\/en\/wp-json\/wp\/v2\/pages\/25006\/revisions\/31871"}],"wp:attachment":[{"href":"https:\/\/cliniqueomicron.ca\/en\/wp-json\/wp\/v2\/media?parent=25006"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}