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Gynecology - Female Genital Infections

Bartholinitis | Clinique Omicron Quebec

Bartholinitis is the inflammation, most often of infectious origin, of one or both of Bartholin's glands. These glands, also called major vestibular glands, are two small glandular structures located on either side of the vaginal opening, at the base of the labia minora. Their role is to produce lubricating mucus to facilitate sexual intercourse. When the excretory duct of one of these glands becomes blocked, mucus accumulates and forms a cyst, which is usually painless. If this cyst becomes infected, it develops into a bartholin gland abscess, characterized by sharp pain, significant swelling, and localized redness. Bartholinitis primarily affects women of childbearing age, with a peak incidence between 20 and 30 years old. It is rarer after menopause, where any vulvar mass must be systematically evaluated to rule out a tumor. In the majority of cases, bartholinitis is caused by bacteria from the normal vaginal flora or sexually transmitted pathogens. Prompt medical management can prevent progression to a large abscess and reduce the risk of recurrence.

Anatomy and Pathophysiology

Understanding the location and function of the Bartholin glands helps to grasp the mechanism of bartholinitis:

  • The Bartholin's glands are about 0.5 to 1 cm in size and are located at the 4 o'clock and 8 o'clock positions on the vaginal orifice clock face.
  • Each gland is connected to the vulvar surface by an excretory duct about 2 cm in length.
  • Blockage of the canal, due to trauma, inflammation, or mucus thickening, leads to cyst formation.
  • Bacterial colonization of the cyst triggers abscess formation with a buildup of pus under pressure.
  • In the absence of drainage, the abscess can reach several centimeters and become very painful, making walking and sitting difficult.

Causes and infectious agents

Bartholinitis is most often polymicrobial. The responsible agents vary depending on whether it is an endogenous flora infection or a sexually transmitted infection:

Category Frequent agents Context
Endogenous vaginal flora Escherichia coli, streptococci, staphylococci, anaerobic bacteria (Bacteroides, Peptostreptococcus) Most common cause, independent of sexual activity
Sexually transmitted infections Neisseria gonorrhoeae (gonorrhea), Chlamydia trachomatis Less frequent, but always to be ruled out by sampling in case of bartholinitis
Other agents Mycoplasma hominis, Ureaplasma urealyticum, Trichomonas vaginalis Agents less frequently involved, detected during expanded microbiological cultures
Non-infectious cause Mechanical obstruction of the canal without secondary infection Formation of a simple cyst, often asymptomatic, without inflammation or fever

Risk factors

Certain situations increase the risk of developing bartholinitis or a Bartholin's gland cyst:

  • History of bartholinitis or bartholin cyst: high risk of recurrence
  • Recurrent or untreated genital infections
  • Unprotected sex with multiple partners: increased risk of STIs
  • Local trauma: waxing, shaving, micro-abrasions
  • Inadequate vulvar hygiene: irritating products, douching disrupting flora
  • Immunosuppression: HIV, poorly controlled diabetes, prolonged corticosteroid therapy
  • Wearing too-tight clothing promotes maceration and local irritation

Symptoms

The clinical presentation varies depending on whether it is a simple uninfected cyst or a developed bartholin abscess:

Stadium Clinical presentation Associated symptoms
Uncomplicated, non-infected cyst Soft, rounded mass, painless or slightly uncomfortable to the touch, located at the base of a labium majus. Often asymptomatic; sensation of discomfort during intercourse or walking if voluminous
Bartholinitis debutante Progressive swelling, localized redness and warmth, pain on palpation Discomfort when walking and sitting, slight sensitivity during intercourse
Bartholin's abscess formed Fluctuating, very painful, red and hot mass, measuring up to 3 to 5 cm or more Intense and pulsating pain, inability to walk or sit normally, possible fever, purulent discharge if spontaneous rupture
Recurrent bartholinitis Recurrence of cyst or abscess in the months following a treated initial episode Symptoms similar to previous episodes; scar tissue that may promote relapses
ℹ️ In menopausal women, any new vulvar mass, even if painless, must be medically evaluated without delay. Although bartholinitis is rare after menopause, a carcinoma of Bartholin's gland, while infrequent, must be formally ruled out by biopsy before any treatment. This rule applies to any woman over 40 years of age presenting with a mass in the Bartholin's region for the first time.

Diagnosis

The diagnosis of bartholinitis is clinical in the majority of cases. Further examinations are indicated to identify the infectious agent and to rule out STIs or a tumorous cause:

  • Complete gynecological examination: vulvar inspection and palpation, mass location and characterization
  • Pus sample during drainage: aerobic and anaerobic bacterial culture for antibiogram
  • STI Screening: NAT (nucleic acid amplification test) for Neisseria gonorrhoeae and Chlamydia trachomatis
  • Blood count if fever or signs of systemic infection: complete blood count, C-reactive protein
  • Blood glucose or HbA1c if it's the first episode in a woman with no history, to rule out diabetes as a contributing factor
  • Biopsy of the cystic wall in any woman over 40 or in case of atypical recurrence

Treatments

Treatment depends on the stage of Bartholin's gland cyst. A simple asymptomatic cyst may not require immediate treatment, while a formed abscess requires surgical drainage.

Treatment Terms and conditions Indications
Simple surveillance Therapeutic abstention with reevaluation Small, asymptomatic simple cyst in a woman under 40 years old
Warm sitz baths Soak in warm water for 10 to 15 minutes, 3 to 4 times a day. Cyst or early abscess; may promote spontaneous drainage and reduce inflammation
Antibiotic therapy Amoxicillin-clavulanate, metronidazole, or doxycycline depending on the suspected or identified agent Documented bacterial infection, associated STI, systemic signs (fever); antibiotics alone are not sufficient to drain a formed abscess
Incision and drainage and marsupialization Surgical incision of the abscess and creation of a permanent opening for continuous drainage of glandular contents Standard treatment for a Bartholin's abscess; performed in consultation or under local anesthesia depending on size and pain
Word catheter Insertion of a small inflatable balloon catheter into the incised abscess, kept in place for 4 to 6 weeks for tract epithelialization Alternative to marsupialization; less invasive technique, usable in an outpatient setting
Removal of the gland (bartholinetomy) Complete surgical excision of the gland under general or regional anesthesia Multiple relapses despite conservative treatments, suspected tumor lesion, refractory form
ℹ️ It is strongly advised against attempting to pierce or drain a Bartholin's gland cyst or abscess yourself. This procedure, performed without sterile conditions, significantly increases the risk of superinfection, bacterial dissemination, and scarring complications. Only a healthcare professional should perform the drainage under appropriate conditions.

Possible complications

In the absence of treatment or in case of inadequate management, several complications can arise:

Complication Description Contributing factors
Abscess or cystic recurrence Recurrence of cyst or abscess after treatment, related to recanalization or reinfection Insufficient drainage, absence of marsupialization, immunocompromised host
Perivulvar cellulite Spread of infection to surrounding soft tissues, with diffuse redness and hardening Large undrained abscess, aggressive germs, immunosuppression
Necrotizing fasciitis Severe and rapidly progressive infection of the deep fascia, which can be life-threatening. Rare but very serious; favored by diabetes, obesity, and immunodeficiency
Persistent dyspareunia Pain during intercourse related to scars or anatomical deformation after repeated infection Multiple recurrences, iterative marsupialization
Undiagnosed ITS Untreated gonorrhea or chlamydia may progress to upper genital tract infection (salpingitis, pelvic peritonitis). Absence of systematic screening during the initial episode
Signs requiring urgent consultation

Certain situations require immediate medical attention: very large abscesses with disabling pain making it impossible to walk or sit, high fever with chills and general deterioration, rapid spread of redness and swelling beyond the vulvar region, or localized skin necrosis suggesting necrotizing fasciitis. These scenarios constitute surgical and infectious emergencies.

If these signs are present, call 911 immediately.

or go to the nearest emergency room without delay. For any abscess or painful cyst without signs of severity, a prompt consultation at Clinique Omicron is recommended.

Consult at Clinique Omicron

Clinique Omicron offers gynecological consultations for the assessment and management of vulvar conditions, including bartholinitis, at several service points in Quebec. A physician or nurse practitioner specializing (IPS) can examine the lesion, order appropriate microbiological samples, initiate antibiotic treatment if indicated, and refer to a gynecologist for surgical drainage or marsupialization if necessary. In-person and telemedicine consultations are available depending on your situation. To make an appointment at one of our branches in Quebec, visit cliniqueomicron.ca.

The content of this page is provided for informational purposes only and is not intended to replace the advice of a qualified healthcare professional. Consult a physician for any symptoms, questions or decisions you may have regarding your health.

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